03622nam 22006492 450 991080773510332120151005020622.01-107-33061-01-107-33622-81-107-32646-X1-107-33456-X1-107-33290-71-139-01877-91-107-33539-6(CKB)2550000001108096(EBL)1139553(OCoLC)841487122(SSID)ssj0000861042(PQKBManifestationID)11475166(PQKBTitleCode)TC0000861042(PQKBWorkID)10913888(PQKB)11470655(UkCbUP)CR9781139018777(MiAaPQ)EBC1139553(Au-PeEL)EBL1139553(CaPaEBR)ebr10740491(CaONFJC)MIL508449(PPN)261331043(EXLCZ)99255000000110809620110216d2013|||| uy| 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierFed-batch cultures principles and applications of semi-batch bioreactors /Henry C. Lim, University of California, Irvine, Hwa Sung Shin, Inha University[electronic resource]Cambridge :Cambridge University Press,2013.1 online resource (xvii, 457 pages) digital, PDF file(s)Cambridge series in chemical engineeringTitle from publisher's bibliographic system (viewed on 05 Oct 2015).0-521-51336-7 1-299-77198-X Includes bibliographical references at the end of each chapters and index.Introduction to fed-batch bioreactors -- Idealised reactors and fed-batch reactors -- Maximisation of reaction rates and fed-batch operation -- Phenomena that favour fed-batch operations -- Classification and characteristics of fed-batch cultures -- Models based on mass balance equations -- Non-equation-based models -- Experimental determination of specific rates -- Optimization via Pontryagin's maximum principle -- Computational techniques -- Optimization of single and multiple isothermal reactions -- Optimization of fed-batch cultures for cell mass production -- Optimization of fed-batch cultures for metabolites -- Simple, intuitive adaptive optimization -- Measurements, estimation and control -- Feasibility assessment and implementable feed rates.Many, if not most, industrially important fermentation and bioreactor operations are carried out in fed-batch mode, producing a wide variety of products. In spite of this, there is no single book that deals with fed-batch operations. This is the first book that presents all the necessary background material regarding the 'what, why and how' of optimal and sub-optimal fed-batch operations. Numerous examples are provided to illustrate the application of optimal fed-batch cultures. This unique book, by world experts with decades of research and industrial experience, is a must for researchers and industrial practitioners of fed-batch processes (modeling, control and optimization) in biotechnology, fermentation, food, pharmaceuticals and waste treatment industries.Cambridge series in chemical engineering.BioreactorsBioreactors.660/.6Lim Henry C.1935-1689483Shin Hwa Sung1974-UkCbUPUkCbUPBOOK9910807735103321Fed-batch cultures4064582UNINA