03359nam 22006255 450 991080619480332120240127073637.0981-9969-99-910.1007/978-981-99-6999-9(CKB)30119416200041(DE-He213)978-981-99-6999-9(MiAaPQ)EBC31093798(Au-PeEL)EBL31093798(EXLCZ)993011941620004120240127d2023 u| 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierChallenges and Solutions Against Visceral Leishmaniasis[electronic resource] /edited by Angamuthu Selvapandiyan, Ruchi Singh, Niti Puri, Nirmal K. Ganguly1st ed. 2023.Singapore :Springer Nature Singapore :Imprint: Springer,2023.1 online resource (XXI, 449 p. 36 illus., 34 illus. in color.) 9789819969982 Module 1_Epidemiology and Surveillances -- Module 2_Omics and Advancement in Diagnosis -- Module 3_Genetics -- Module 4_New Drug Discovery Opportunity -- Module 5_Immunity and Vaccine Development.This book comprehensively reviews the epidemiology and surveillance strategies of Visceral Leishmaniasis, and the latest developments in disease diagnosis, drug discovery, and vaccine development. The initial chapters cover the epidemiology features and spatial distribution of Visceral Leishmaniasis. The book further discusses the manifestations of HIV-Visceral Leishmaniasis infection on the immunopathogenesis, diagnosis, and therapeutic response. It analyzes the role of different proteomic technologies in understanding the parasite development, survival, drug resistance mechanisms, host-pathogen interactions, and the development of new therapeutic approaches. The book concludes by discussing recent advancements in vaccine development for Visceral Leishmaniasis. It discusses the promising vaccine candidate, their developmental status, current challenges, and prospects for rational vaccine development against Leishmania. This book is an invaluable source of information for students, and researchers working to understand the Leishmania biology, and drug development.ParasitologyDrugsDesignPharmaceutical chemistryEpidemiologyParasitologyStructure-Based Drug DesignPharmaceuticsEpidemiologyParasitology.DrugsDesign.Pharmaceutical chemistry.Epidemiology.Parasitology.Structure-Based Drug Design.Pharmaceutics.Epidemiology.571.999Selvapandiyan Angamuthuedthttp://id.loc.gov/vocabulary/relators/edtSingh Ruchiedthttp://id.loc.gov/vocabulary/relators/edtPuri Nitiedthttp://id.loc.gov/vocabulary/relators/edtGanguly Nirmal Kedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910806194803321Challenges and Solutions Against Visceral Leishmaniasis3907851UNINA