03145nam 22006495 450 991079921170332120251009100943.09783031463532303146353610.1007/978-3-031-46353-2(MiAaPQ)EBC31051702(Au-PeEL)EBL31051702(CKB)29510372300041(OCoLC)1416748334(DE-He213)978-3-031-46353-2(EXLCZ)992951037230004120231214d2023 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierUnderstanding Kinetic Resolution by Hydrolases Maximizing Enantioselectivity /by Abir B. Majumder, Kalluri V. S. Ranganath1st ed. 2023.Cham :Springer Nature Switzerland :Imprint: Springer,2023.1 online resource (57 pages)SpringerBriefs in Molecular Science,2191-5415Print version: Majumder, Abir B. Understanding Kinetic Resolution by Hydrolases Cham : Springer International Publishing AG,c2024 9783031463525 Understanding Enzymatic Kinetic Resolution -- Essential Parameters: Determination and Significance - Enantioselectivity: The Decisive Factors -- Dynamic Kinetic Resolution.This brief is a concise guide that explores the theory and practical aspects of improving enantioselectivity in enzymatic kinetic resolution, with a specific focus on the role of hydrolases in this process. Enzymatic kinetic resolution is a valuable technique for obtaining enantiopure compounds, and hydrolases are highlighted as a crucial class of enzymes widely used in industries for chiral synthesis involving kinetic resolution. The book emphasizes the importance of tuning and optimizing the enzymatic kinetic resolution process to achieve the highest possible enantiomeric excess in the final product or starting material while maintaining the desired yield. Through illustrative examples, the text aims to make the concept accessible and appealing to graduate students, researchers, and young organic chemists seeking to incorporate hydrolases in their stereoselective synthesis endeavors.SpringerBriefs in Molecular Science,2191-5415Bioorganic chemistryCatalysisChemistry, OrganicCatalystsBioorganic ChemistryCatalysisOrganic ChemistryCatalyst SynthesisBioorganic chemistry.Catalysis.Chemistry, Organic.Catalysts.Bioorganic Chemistry.Catalysis.Organic Chemistry.Catalyst Synthesis.572.793Majumder Abir B1586243Ranganath Kalluri V. S1586244MiAaPQMiAaPQMiAaPQBOOK9910799211703321Understanding Kinetic Resolution by Hydrolases3872593UNINA