05654nam 2200697 450 991079725880332120200520144314.00-12-801317-6(CKB)3710000000416572(EBL)2056909(OCoLC)910447567(SSID)ssj0001568587(PQKBManifestationID)16218617(PQKBTitleCode)TC0001568587(PQKBWorkID)14836193(PQKB)10211352(MiAaPQ)EBC2056909(Au-PeEL)EBL2056909(CaPaEBR)ebr11058681(CaONFJC)MIL788492(OCoLC)910159094(PPN)19678588X(EXLCZ)99371000000041657220150721h20152015 uy| 0engur|n|---|||||txtccrNanotechnology in diagnosis, treatment and prophylaxis of infectious diseases /edited by Mahendra Rai, Biotechnology Department, SGB Amravati University, Amravati, Maharashtra, India, Kateryna Kon, Department of Microbiology, Virology and Immunology, Kharkiv National Medical University, Kharkiv, UkraineAmsterdam :Elsevier,[2015]©20151 online resource (361 p.)Description based upon print version of record.0-12-801471-7 Includes bibliographical references and index.""Front Cover""; ""Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases""; ""Copyright Page""; ""Contents""; ""List of Contributors""; ""Preface""; ""1 Gold and Silver Nanoparticles for Diagnostics of Infection""; ""1.1 Nanotechnology and Infection""; ""1.2 Gold and Silver NPs for Molecular Diagnostics""; ""1.2.1 Biomarkers""; ""1.3 Nanodiagnostics for Nucleic Acids""; ""1.3.1 Homogeneous Colorimetric Assays""; ""1.3.1.1 Unmodified NPs""; ""1.3.1.2 Cross-Linking""; ""1.3.1.3 Noncross-Linking""; ""1.3.2 Heterogeneous Detection""; ""1.3.2.1 Microarrays""""1.3.2.2 Lateral Flow Assays""""1.3.3 Electrochemical Assays""; ""1.3.4 Fluorescence Assays""; ""1.3.5 Raman and SERS""; ""1.3.6 Other""; ""1.4 Aptamers and Antibodies""; ""1.4.1 Colorimetric""; ""1.4.2 Electrochemical""; ""1.4.3 Lateral Flow Assays""; ""1.5 iPCR and Other Methods""; ""1.6 Conclusion""; ""References""; ""2 Antimicrobial Models in Nanotechnology: From the Selection to Application in the Control and Treatment of Infectious Diseases""; ""2.1 Introduction""; ""2.2 Antimicrobial Susceptibility Testing Methods of NMs""; ""2.2.1 Broth Dilution Test""""2.2.2 Spectrophotometric Measurement""""2.2.3 Cell Counting""; ""2.2.4 Colorimetric and Fluorescent Assays""; ""2.2.5 In Vitro Infection Animal Model""; ""2.2.6 Biocidal Testing""; ""2.2.7 Antibiofilm Activity""; ""2.2.8 Quorum-Sensing Inhibitors""; ""2.2.9 Microbial Membrane Lysis""; ""2.2.10 Microbial Oxidative Stress""; ""2.2.11 Antipersister and Antidormancy Bacterial Cells""; ""2.2.12 Microbial Fitness""; ""2.3 Nanotoxicology""; ""2.3.1 Nano-Genotoxicology""; ""2.3.2 Cytotoxicity""; ""2.3.3 Immunotoxicity""; ""2.3.4 In Vitro Skin Irritation""""2.3.5 Caenorhabditis elegans Toxicity Model""""2.3.6 Nanotoxicity in Embryonic and Adult Zebrafish""; ""2.3.7 Bioluminescence-Based Nanotoxicity Test""; ""2.4 In Vitro Pharmacokinetics/Pharmacodynamic Models""; ""2.4.1 Particokinetics""; ""2.4.2 Caco-2 Permeability""; ""2.4.3 Hollow Fiber System""; ""2.5 Conclusions""; ""References""; ""3 Silver Nanoparticles for the Control of Vector-Borne Infections""; ""3.1 Introduction""; ""3.2 Louse-Borne Infections and Activity of AgNPs Against Lice""; ""3.3 Mosquito-Borne Infections and Activity of AgNPs Against Mosquitoes""""3.4 Tick-Borne Infections and Activity of AgNPs Against Ticks""""3.5 Flies, Their Role in Transmission and Spread of Infections, and Activity of AgNPs Against Flies""; ""3.6 Conclusions and Future Prospects""; ""References""; ""4 Magnetite Nanostructures: Trends in Anti-Infectious Therapy""; ""4.1 Introduction""; ""4.2 Nanoparticles with Biomedical Applications""; ""4.2.1 Design of Tailored Magnetic Nanoparticles with Applications in Microbiology""; ""4.2.2 Magnetite Nanoparticles Used to Control Microorganisms Attachment and Biofilm Formation""""4.2.3 The Biocompatibility of Magnetite Nanoparticles"" Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising NanotechnologyHealth aspectsMedical technologyNanomedicineCommunicable diseasesNanotechnologyHealth aspects.Medical technology.Nanomedicine.Communicable diseases.612.8252Rai MahendraKon KaterynaMiAaPQMiAaPQMiAaPQBOOK9910797258803321Nanotechnology in diagnosis, treatment and prophylaxis of infectious diseases3783494UNINA