00999nam 2200361 450 991079456730332120230630002930.00-88977-704-7(CKB)4100000011922576(MiAaPQ)EBC6578932(EXLCZ)99410000001192257620220602d2021 uy 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierGather Richard Van Camp on the joy of storytelling /Richard Van CampRegina, Saskatchewan, Canada :University of Regina Press,[2021]©20211 online resource (194 pages)0-88977-700-4 StorytellingStorytelling.808.543Van Camp Richard1110304MiAaPQMiAaPQMiAaPQBOOK9910794567303321Gather3684272UNINA05157nam 22006375 450 991029835210332120200703215134.01-4939-1598-310.1007/978-1-4939-1598-9(CKB)3710000000291286(EBL)1968644(OCoLC)896824888(SSID)ssj0001385802(PQKBManifestationID)11994423(PQKBTitleCode)TC0001385802(PQKBWorkID)11349390(PQKB)11165203(MiAaPQ)EBC1968644(DE-He213)978-1-4939-1598-9(PPN)18309140X(EXLCZ)99371000000029128620141121d2014 u| 0engur|n|---|||||txtccrAmorphous Solid Dispersions Theory and Practice /edited by Navnit Shah, Harpreet Sandhu, Duk Soon Choi, Hitesh Chokshi, A. Waseem Malick1st ed. 2014.New York, NY :Springer New York :Imprint: Springer,2014.1 online resource (702 p.)Advances in Delivery Science and Technology,2192-6204Description based upon print version of record.1-4939-1597-5 Includes bibliographical references at the end of each chapters and index.1 Fundamentals of Amorphous Systems: Thermodynamic Aspects -- 2 Theoretical Considerations in Developing Amorphous Solid Dispersions -- 3 Overview of Amorphous Solid Dispersion Technologies -- 4 Excipients for Amorphous Solid Dispersions -- 5 Miniaturized Screening Tools for Polymer and Process Evaluation -- 6 HME for Solid Dispersions: Composition and Design Considerations -- 7 HME for Solid Dispersions: Scale up and Late Stage Development -- 8 Spray Drying: Scale UP and Manufacturing -- 9 Design and Development of HPMCAS based spray dried dispersions -- 10 MBP Technology: Composition and Design Considerations -- 11 MBP Technology: Process Development and Scale up -- 12 Pharmaceutical Development of MBP Solid Dispersions: Case Studies -- 13 Downstream Processing Considerations -- 14 Structural Characterization of Amorphous Solid Dispersions -- 15 Dissolution of Amorphous Solid Dispersions: Theory and Practice -- 16 Stability of Amorphous Solid Dispersion -- 17 Regulatory Considerations in Development of Amorphous Solid Dispersions -- 18 KinetiSol® based Amorphous Solid Dispersions -- 19 Amorphous Solid Dispersion Using Supercritical Fluid Technology -- 20 Supersolubilization by Using Non-Salt Forming Acid-Base Interaction -- 21 Stabilized Amorphous Solid Dispersions with Small Molecule Excipients -- 22 Mesoporous ASD – Fundamentals -- 23 Mesoporous Silica Drug Delivery Systems.This volume offers a comprehensive guide on the theory and practice of amorphous solid dispersions (ASD) for handling challenges associated with poorly soluble drugs. In twenty-three inclusive chapters, the book examines thermodynamics and kinetics of the amorphous state and amorphous solid dispersions, ASD technologies, excipients for stabilizing amorphous solid dispersions such as polymers, and ASD manufacturing technologies, including spray drying, hot melt extrusion, fluid bed layering and solvent-controlled micro-precipitation technology (MBP). Each technology is illustrated by specific case studies. In addition, dedicated sections cover analytical tools and technologies for characterization of amorphous solid dispersions, the prediction of long-term stability, and the development of suitable dissolution methods and regulatory aspects. The book also highlights future technologies on the horizon, such as supercritical fluid processing, mesoporous silica, KinetiSol®, and the use of non-salt-forming organic acids and amino acids for the stabilization of amorphous systems. Amorphous Solid Dispersions: Theory and Practice is a valuable reference to pharmaceutical scientists interested in developing bioavailable and therapeutically effective formulations of poorly soluble molecules in order to advance these technologies and develop better medicines for the future. .Advances in Delivery Science and Technology,2192-6204Pharmaceutical technologyPharmaceutical Sciences/Technologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B21010Pharmaceutical technology.Pharmaceutical Sciences/Technology.615.7Shah Navnitedthttp://id.loc.gov/vocabulary/relators/edtSandhu Harpreetedthttp://id.loc.gov/vocabulary/relators/edtChoi Duk Soonedthttp://id.loc.gov/vocabulary/relators/edtChokshi Hiteshedthttp://id.loc.gov/vocabulary/relators/edtMalick A. Waseemedthttp://id.loc.gov/vocabulary/relators/edtControlled Release Society,MiAaPQMiAaPQMiAaPQBOOK9910298352103321Amorphous Solid Dispersions2539487UNINA00817nam a2200229 i 450099100438153210753620250515133253.0250515s1999 it a er 001 0 ita d8817990396Bibl. Dip.le Aggr. Studi Umanistici - Sez. FilosofiaitaSocioculturale Scsita070.5094523.Rizzoli <casa editrice>437863150. BUR :1949-1999 : catalogo storico1949-1999 : catalogo storicoMillenovecentoquarantanove-millenovecentonovantanoveMilano :Biblioteca universale Rizzoli,[1999]XLIV, 681 p., [4] carte di tav. :ill. ;20 cmRizzoli <casa editrice>1949-1999Cataloghi991004381532107536Rizzoli4378631UNISALENTO