02029nam 2200409z- 450 991026114350332120231214133351.0(CKB)4100000002484657(oapen)https://directory.doabooks.org/handle/20.500.12854/43699(EXLCZ)99410000000248465720202102d2017 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierComputational and Experimental Approaches in Multi-Target PharmacologyFrontiers Media SA20171 electronic resource (122 p.)Frontiers Research Topics2-88945-252-2 The next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that underlies pathological processes. It will also require the development of single drugs with multiple targets, or combinations of drugs with compatible pharmacokinetics that work synergistically to maximize desirable effects while minimizing unwanted side effects. This e-Book contains ten original articles, each addressing a different aspect of this challenge. Together they open new perspectives and show the way forward in the development of multi-target therapeutics.systems biologycomputer modelingdrug repurposingsynergydrug discoverydrug combinationhigh throughput screeningmultidrug therapeuticspolypharmacymultifactorial processThomas J. Anastasioauth1279228BOOK9910261143503321Computational and Experimental Approaches in Multi-Target Pharmacology3014843UNINA01025nam 2200349 450 99107925633033212-8062-8326-4(CKB)3710000001007987(MiAaPQ)EBC4775536(PPN)261782967(EXLCZ)99371000000100798720170116h20162016 uy| 0freurcnu||||||||rdacontentrdamediardacarrierOscar et la Dame rose d'Éric-Emmanuel Schmitt analyse de l'œuvre /par Laure de Caevel et Lucile Lhoste[Paris] :LePetitLittéraire.fr,[2016]©20161 online resource (22 pages)Fiche de lectureFiche de lecture.Caevel Laure de1492900Lhoste LucileMiAaPQMiAaPQMiAaPQBOOK9910792563303321Oscar et la Dame rose d'Éric-Emmanuel Schmitt3715648UNINA