01299nam0 22003011i 450 VAN000927520050831120000.088-14-06337-0IT97 659620020913d1996 |0itac50 baitaIT|||| |||||ˆGli ‰atti amministrativi dichiarativiaspetti sostanziali e profili di tutelaPiero GottiMilanoGiuffrè1996299 p.24 cm.001VAN00036162001 Pubblicazioni della Facoltà di giurisprudenzaUniversità di Firenze210 MilanoGiuffrè.78Atti amministrativiVANC000029FIMilanoVANL000284342.45066Procedimento amministrativo. Italia21GottiPieroVANV007323239186Giuffrè <editore>VANV109181650ITSOL20230616RICAVAN0009275BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA00CONS IV.Eg.48 00 14219 20021113 BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA00CONS IV.Eg.48 bis 00 210600219 20021114 Atti amministrativi dichiarativi627099UNICAMPANIA03313nam 2200637 a 450 991079205880332120200520144314.01-299-27682-22-84254-237-110.1051/978-2-84254-237-5(CKB)2560000000099461(EBL)3155343(SSID)ssj0000906519(PQKBManifestationID)11536131(PQKBTitleCode)TC0000906519(PQKBWorkID)10843950(PQKB)10824750(MiAaPQ)EBC3155343(Au-PeEL)EBL3155343(CaPaEBR)ebr10667713(CaONFJC)MIL458932(OCoLC)922991221(DE-B1597)634993(DE-B1597)9782842542375(MiAaPQ)EBC7156049(Au-PeEL)EBL7156049(OCoLC)1355220062(OCoLC)834607434(PPN)176628622(EXLCZ)99256000000009946120130313d2012 uy 0engur|n|---|||||txtccrThe clinibook[electronic resource] clinical gene transfer : state of the art /edited by Odile Cohen-HaguenauerParis EDP Sciences20121 online resource (589 p.)Description based upon print version of record.2-84254-171-5 Includes bibliographical references and index.pt. 1. Technologies and pre-clinical studies -- pt. 2. Clinical trials and regulatory issues.This book provides a 2012 reference for state-of-the-art gene transfer technology and the different aspects of its clinical translation with a focus on European-based initiatives. As examples of successful outcomes, recent clinical trials are presented together with Ethical, Safety and Regulatory issues, which are discussed. The broad range of various technologies is covered whether addressing direct in vivo gene transfer like with AAV, Adeno or non-viral vectors or ex-vivo genetically engineered cells including induced pluripotent stem cells (iPS) with integrating vectors such as retrovirus, lentivirus or transposon-derived systems. The critical path to clinical implementation is covered in the second part describing currently available tools - such as molecular imaging, ex-vivo organ cultures and high-throughput technologies used for evaluation of criteria towards a go-or-no go decision to move to the clinic; in addition, utmost salient biosafety and immunotoxicology aspects are discussed. This book is ideal for postgraduates, undergraduates, scientists, clinicians, regulators and patients' advocacy groups looking for states-of-the-art information as well as emerging prospects - including gene targeting and homologous recombination - in gene transfer intended for clinical translation.Genetic transformationGenetic transformation.571.96Cohen-Haguenauer Odile, authttp://id.loc.gov/vocabulary/relators/aut1087562Cohen-Haguenauer Odile1087562MiAaPQMiAaPQMiAaPQBOOK9910792058803321The clinibook3823776UNINA03609nam 22007455 450 991048322610332120200705110535.03-319-61473-810.1007/978-3-319-61473-1(CKB)4340000000061605(DE-He213)978-3-319-61473-1(MiAaPQ)EBC5578615(PPN)203668545(EXLCZ)99434000000006160520170619d2017 u| 0engurnn#008mamaatxtrdacontentcrdamediacrrdacarrierTheory and Practice of Model Transformation 10th International Conference, ICMT 2017, Held as Part of STAF 2017, Marburg, Germany, July 17-18, 2017, Proceedings /edited by Esther Guerra, Mark van den Brand1st ed. 2017.Cham :Springer International Publishing :Imprint: Springer,2017.1 online resource (XIV, 183 p. 73 illus.)Programming and Software Engineering ;10374Includes index.3-319-61472-X This book constitutes the refereed proceedings of the 10th International Conference on Model Transformation, ICMT 2017, held as part of STAF 2017, in Marburg, Germany, in July 2017. The 9 full papers and 2 short papers were carefully reviewed and selected from 31 submissions. The papers are organized in the following topical sections: transformation paradigms, languages, algorithms and strategies; development of transformations; and applications and case studies.Programming and Software Engineering ;10374Software engineeringOperating systems (Computers)Logic designManagement information systemsComputer scienceArchitecture, ComputerProgramming languages (Electronic computers)Software Engineeringhttps://scigraph.springernature.com/ontologies/product-market-codes/I14029Operating Systemshttps://scigraph.springernature.com/ontologies/product-market-codes/I14045Logic Designhttps://scigraph.springernature.com/ontologies/product-market-codes/I12050Management of Computing and Information Systemshttps://scigraph.springernature.com/ontologies/product-market-codes/I24067Computer System Implementationhttps://scigraph.springernature.com/ontologies/product-market-codes/I13057Programming Languages, Compilers, Interpretershttps://scigraph.springernature.com/ontologies/product-market-codes/I14037Software engineering.Operating systems (Computers).Logic design.Management information systems.Computer science.Architecture, Computer.Programming languages (Electronic computers).Software Engineering.Operating Systems.Logic Design.Management of Computing and Information Systems.Computer System Implementation.Programming Languages, Compilers, Interpreters.005.1Guerra Estheredthttp://id.loc.gov/vocabulary/relators/edtvan den Brand Markedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910483226103321Theory and Practice of Model Transformation2095766UNINA