04387nam 2200625 a 450 991079184160332120230725021051.00-309-16157-61-282-78754-397866127875460-309-15655-6(CKB)2560000000067684(EBL)3378669(SSID)ssj0000417460(PQKBManifestationID)11290802(PQKBTitleCode)TC0000417460(PQKBWorkID)10361701(PQKB)10274707(MiAaPQ)EBC3378669(Au-PeEL)EBL3378669(CaPaEBR)ebr10420228(CaONFJC)MIL278754(OCoLC)923282191(EXLCZ)99256000000006768420101105d2010 uy 0engurcn|||||||||txtccrExtending the spectrum of precompetitive collaboration in oncology research[electronic resource] workshop summary /Margie Patlak, Sharyl J. Nass and Erin Balogh, rapporteurs ; National Cancer Policy Forum, Board on Health Care Services, Institute of Medicine of the National AcademiesWashington, D.C. National Academies Press20101 online resource (113 p.)Description based upon print version of record.0-309-15654-8 Includes bibliographical references.""Front Matter""; ""Reviewers""; ""Contents""; ""Boxes, Figures, and Tables""; ""Workshop Summary""; ""Acronyms""; ""Glossary""; ""Appendix A: Workshop Agenda""; ""Appendix B: Polling Results"""Despite spending more time and money in developing novel therapeutics, the success rate for new pharmacologic treatments has been poor. Although the research and development expenditures have grown 13 percent each year since 1970 (a 50-fold increase), the number of new drugs approved annually is no greater now than it was 50 years ago. Over the past decade, skyrocketing costs and the complexity of the scientific knowledge upon which to develop new agents have provided incentives for alternative approaches to drug development, if we are to continue to improve clinical care and reduce mortality. These challenges create opportunities for improved collaboration between industry, academia, government, and philanthropic organizations at each stage in new drug development, marketing, and implementation. Perhaps the most appropriate initial step in addressing the need for collaboration is to consider more precompetitive relationships that allow sharing of scientific information to foster drug development.While these collaborative relationships in basic and preclinical research on drug targets and the early stages of clinical testing are acknowledged to be potentially important drivers for innovation and more rapid marketing of new agents, they also raise a number of concerns that must be addressed. For example, acknowledgment of academic productivity and independence and economic competitiveness must be considered and these challenges managed to foster a culture of collaboration. At the same time, regulatory issues, the need for standardization, and intellectual property concerns must be confronted if the current models for drug development are to be refined to encourage robust participation in precompetitive collaborations. Recognizing the growing importance of precompetitive collaborations in oncology drug development, as well as the challenges these innovative collaborations pose, the National Cancer Policy Forum of the Institute of Medicine held a workshop on February 9 and 10, 2010. This book is a summary of the workshop proceedings."--Publisher's description.OncologyResearchCongressesOncologyResearch616.994Patlak Margie1476477Patlak Margie1476477Nass Sharyl J857626Balogh Erin1089066National Cancer Policy Forum (U.S.)Institute of Medicine (U.S.).Board on Health Care Services.MiAaPQMiAaPQMiAaPQBOOK9910791841603321Extending the spectrum of precompetitive collaboration in oncology research3691153UNINA