03141nam 2200613Ia 450 991079147730332120230725015616.00-309-15727-71-282-78742-X97866127874230-309-15130-9(CKB)2560000000015980(EBL)3378636(SSID)ssj0000417279(PQKBManifestationID)11267613(PQKBTitleCode)TC0000417279(PQKBWorkID)10361258(PQKB)10448333(MiAaPQ)EBC3378636(Au-PeEL)EBL3378636(CaPaEBR)ebr10405099(CaONFJC)MIL278742(OCoLC)923281847(EXLCZ)99256000000001598020100511d2010 uy 0engurcn|||||||||txtccrEvaluation of biomarkers and surrogate endpoints in chronic disease[electronic resource] /Committee on Qualification of Biomarkers and Surrogate Endpoints in Chronic Disease, Board on Health Care Services, Board on Health Sciences Policy, Food and Nutrition Board, Institute of Medicine ; Christine M. Micheel and John R. Ball, editorsWashington, DC National Academies Pressc20101 online resource (335 p.)Description based upon print version of record.0-309-15129-5 Includes bibliographical references.""Front Matter""; ""Reviewers""; ""Preface""; ""Acknowledgments""; ""Contents""; ""Boxes, Figures, and Tables""; ""Summary""; ""1 Introduction""; ""2 Review: Evaluating and Regulating Biomarker Use""; ""3 The Biomarker Evaluation Process""; ""4 Case Studies""; ""5 Strengthening Evidence-Based Regulation""; ""Acronyms""; ""Glossary""; ""Appendix A: Table of Papers About Biomarker Qualification""; ""Appendix B: Recommendations from Related IOM Reports""; ""Appendix C: Committee Member and Consultant Biographies""; ""Appendix D: Staff Biographies""; ""Appendix E: Workshop Agenda""""Appendix F: Speaker Biographies"""Many people naturally assume that the claims made for foods and nutritional supplements have the same degree of scientific grounding as those for medication, but that is not always the case. The IOM recommends that the FDA adopt a consistent scientific framework for biomarker evaluation in order to achieve a rigorous and transparent process."--Publisher's description.Biochemical markersEvaluationChronic diseasesBiochemical markersEvaluation.Chronic diseases.610.28Micheel Christine1484237Ball John1944-1493792Institute of Medicine (U.S.).Committee on Qualification of Biomarkers and Surrogate Endpoints in Chronic Disease.MiAaPQMiAaPQMiAaPQBOOK9910791477303321Evaluation of biomarkers and surrogate endpoints in chronic disease3719241UNINA