03930nam 2201213z- 450 991059507410332120231214133347.0(CKB)5680000000080785(oapen)https://directory.doabooks.org/handle/20.500.12854/92098(EXLCZ)99568000000008078520202209d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierDelivery of Molecules Using Nanoscale Systems for Cancer Treatment and/or DiagnosisBaselMDPI Books20221 electronic resource (302 p.)3-0365-4961-7 3-0365-4962-5 This book focuses on how nanoscale systems can be used to deliver molecules to help with cancer management. It provides a broad overview of some of the key strategies for nanocarrier design. These strategies are brought together by the wide compositional variety of these systems and the diversity of molecules that may be carried. Additionally, functionalization strategies, codelivery, and combination with other treatment modalities highlight a very active research field.MedicinebicsscPharmacologybicsscnanostructured lipid carriersdoxorubicinmucositiscell internalizationalbuminBSACPPgold nanorodsgold nanoprismsarginine-rich peptideglutathionenanoparticlesoxidative stressbreast cancergastric cancernanoparticlefucoidand-alpha-tocopherylpoly (ethylene glycol) succinatecombination chemotherapyG-quadruplexnucleolinDNA nanocagesintracellular localizationcancer targetingmolecular dynamics simulationsmesoporous silica nanoparticlesradiotherapyimmunotherapytumor microenvironmentabscopal effectmagnetofection in vivomagnetic nanoparticlesiron oxidegene deliverygene vectorscodelivery nanocarriersphotodynamic therapyanticancer therapiescombination therapyphthalocyanineuterine cervical neoplasmsphotochemotherapyin vitroin vivonanocarrierpolyplexessiRNA deliveryglioblastoma therapyamphiphilic poly(α)glutamateP-selectinprodrugdrug deliverytargeted therapychemotherapyprostate cancerprostate-specific membrane antigentargeted deliveryencapsulationcabazitaxelnanocarriersnanosystemsradiosensitizerhypoxiasynergismcancerphotothermal therapycombined antitumor effectoxygenationhydrogelhypoxic tumorMedicinePharmacologyFranco Marina Santiagoedt1328471Youn Yu SeokedtFranco Marina SantiagoothYoun Yu SeokothBOOK9910595074103321Delivery of Molecules Using Nanoscale Systems for Cancer Treatment and3038577UNINA06012nam 2200985 450 991079103370332120230830123741.00-520-27754-60-520-95842-X10.1525/9780520958425(CKB)2550000001297955(EBL)1686846(SSID)ssj0001236118(PQKBManifestationID)11680005(PQKBTitleCode)TC0001236118(PQKBWorkID)11232387(PQKB)10823538(MiAaPQ)EBC1686846(OCoLC)879946702(MdBmJHUP)muse32324(DE-B1597)521150(OCoLC)1102803787(DE-B1597)9780520958425(Au-PeEL)EBL1686846(CaPaEBR)ebr10871933(CaONFJC)MIL608369(EXLCZ)99255000000129795520140531h20142014 uy 0engur|n|---|||||txtccrBreadlines knee deep in wheat food assistance in the great depression /Janet Poppendieck ; foreword by Marion NestleUpdated and expanded edition.Berkeley ;Los Angeles, California :University of California Press,2014.©20141 online resource (401 p.)California Studies in Food and Culture ;53Includes index.0-520-27753-8 1-306-77118-8 Frontmatter --Contents --Foreword --Acknowledgments --Introduction: The Paradox of Want amid Plenty --List of Abbreviations --One. The Plight of the Farmer --Two. Depression: Deprivation and Despair --Three. The Politics of Wheat and Drought --Four. Government Grain for the Needy --Five. The End of the Hoover Era --Six. The Promise of the New Deal --Seven. The Little Pigs: The Genesis of Relief Distribution --Eight. The Federal Surplus Relief Corporation --Nine. The Corporation in Conflict: Competition with Private Enterprise --Ten. Transfer to the Department of Agriculture --Eleven. Accommodation to Agricultural Priorities --Twelve. Food Assistance: The Legacy of New Deal Policy Choices --Epilogue --Acknowledgments to the 2014 Edition --Sources --Notes --IndexAt no time during the Great Depression was the contradiction between agriculture surplus and widespread hunger more wrenchingly graphic than in the government's attempt to raise pork prices through the mass slaughter of miliions of "unripe" little pigs. This contradiction was widely perceived as a "paradox." In fact, as Janet Poppendieck makes clear in this newly expanded and updated volume, it was a normal, predictable working of an economic system rendered extreme by the Depression. The notion of paradox, however, captured the imagination of the public and policy makers, and it was to this definition of the problem that surplus commodities distribution programs in the Hoover and Roosevelt administrations were addressed. This book explains in readable narrative how the New Deal food assistance effort, originally conceived as a relief measure for poor people, became a program designed to raise the incomes of commercial farmers. In a broader sense, the book explains how the New Deal years were formative for food assistance in subsequent administrations; it also examines the performance--or lack of performance--of subsequent in-kind relief programs. Beginning with a brief survey of the history of the American farmer before the depression and the impact of the Depression on farmers, the author describes the development of Hoover assistance programs and the events at the end of that administration that shaped the "historical moment" seized by the early New Deal. Poppendieck goes on to analyze the food assistance policies and programs of the Roosevelt years, the particular series of events that culminated in the decision to purchase surplus agriculture products and distribute them to the poor, the institutionalization of this approach, the resutls achieved, and the interest groups formed. The book also looks at the takeover of food assistance by the U.S. Department of Agriculture and its gradual adaptation for use as a tool in the maintenance of farm income. Utliizing a wide variety of official and unofficial sources, the author reveals with unusual clarity the evolution from a policy directly responsive to the poor to a policy serving mainly democratic needs.Food reliefUnited StatesHistoryDepressions1929United StatesAgriculture and stateUnited StatesHistory20th century american history.agricultural surplus.american government.american history.breadlines.california studies in food and culture series.commercial farmers.cultural studies.economic system.fdr.food assistance.government.great depression.history.hoover administration.hunger.new deal food assistance effort.new deal programs.policy makers.president franklin d roosevelt.president herbert hoover.roosevelt administration.surplus commodities.us department of agriculture.widespread hunger.Food reliefHistory.DepressionsAgriculture and stateHistory.363.8830973Poppendieck Janet1945-,1026169Nestle MarionMiAaPQMiAaPQMiAaPQBOOK9910791033703321Breadlines knee deep in wheat3817396UNINA06696nam 22007935 450 991029967560332120200629204151.03-319-26473-710.1007/978-3-319-26473-8(CKB)3710000000532713(EBL)4189350(SSID)ssj0001597198(PQKBManifestationID)16298243(PQKBTitleCode)TC0001597198(PQKBWorkID)14885291(PQKB)11628310(DE-He213)978-3-319-26473-8(MiAaPQ)EBC4189350(PPN)190886781(EXLCZ)99371000000053271320151212d2015 u| 0engur|n|---|||||txtccrA Conceptual Model for Designing Recycled Aggregate Concrete for Structural Applications /by Marco Pepe1st ed. 2015.Cham :Springer International Publishing :Imprint: Springer,2015.1 online resource (178 p.)Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053"Doctoral Thesis accepted by University of Salerno, Italy"--Title page.3-319-26472-9 Includes bibliographical references at the end of each chapters.Parts of this thesis have been published in the following journal articles:; Supervisor's Foreword; Acknowledgments; Contents; Symbols and Abbreviations; About the Author; 1 Introduction; 1.1 Motivation; 1.2 Main Contributions; 1.3 Thesis Outline; References; 2 Concrete Industry: Waste Generation and Environmental Concerns; 2.1 Construction and Demolition Waste; 2.2 Concrete and Construction Industry: Aggregates Sources; 2.3 Concrete and Construction Industry: Cement Production; References; 3 Regulatory Environment and Guidelines for RACs; 3.1 The Italian Code for Constructions3.2 RILEM Recommendations3.3 DAfStb Guidelines and DIN Standards; 3.4 British Standards; 3.5 Buildings Department of the Hong Kong; 3.6 American Concrete Institute; 3.7 Cement Concrete and Aggregates Australia; 3.8 Main Conclusions Drawn from Existing Regulations and Standards; References; 4 Recycled Concrete Aggregates; 4.1 State of the Art for Recycled Concrete Aggregates (RCAs); 4.1.1 Processing Procedures; 4.1.2 Attached Mortar Evaluation; 4.1.3 Engineering Properties of RCAs; 4.2 Physical and Mechanical Characterisation of RCAs; 4.2.1 Attached Mortar Content4.2.2 Porosity, Water Absorption and Particle Density4.2.3 Mechanical Strength; 4.2.4 Bond Strength Between Aggregates and Cement Paste; 4.3 Alternative Processing Procedures for RCAs; References; 5 Recycled Aggregate Concretes; 5.1 Basic Aspects About Concrete Mix Design and Technology; 5.1.1 The Role of Aggregates in Concrete Mixture; 5.1.2 Portland Cement; 5.1.3 Influence of Moisture Content and w/c Ratio; 5.1.4 Curing Conditions; 5.2 State of the Art for Recycled Aggregate Concrete (RAC); 5.2.1 Workability; 5.2.2 Compressive Strength; 5.2.3 Static Modulus of Elasticity5.2.4 Tensile and Flexural Strength5.2.5 Drying Shrinkage; 5.3 Experimental Activities; 5.3.1 Influence of Alternative Processing Procedures on RCAs; 5.3.2 Influence of the Initial Moisture Condition of RCAs; 5.3.3 Influence of the Aggregate Replacement and Water to Cement Ratios; References; 6 Insights into the Influence of Cement Replacement in Recycled Aggregate Concrete; 6.1 Fly Ash in Recycled Aggregate Concrete; 6.1.1 Workability; 6.1.2 Compressive Strength; 6.1.3 Alkali-Silica Reaction; 6.1.4 Carbonation Depth; 6.1.5 Chloride Ion Penetration Resistance; 6.2 Experimental Activities6.2.1 Mix Composition and Experimental Programme6.2.2 Analysis of the Results; 6.3 Empirical Relationships for Compressive Strength of RAC+Fly Ash; 6.4 Conclusions; References; 7 Predicting the Mechanical Properties of RAC; 7.1 Compressible Packing Model; 7.1.1 Theoretical Formulation; 7.1.2 Application; 7.2 Lattice Model; 7.2.1 Theoretical Formulation; 7.2.2 Application; 7.3 A Proposed Conceptual Model for RACs; 7.3.1 Hydration Model; 7.3.2 Proposed Formulations for Predicting the Strength of RAC; 7.3.3 Model Validation; References; 8 Mix Design Formulation for RAC8.1 Conceptual Model Flow ChartThis book reports on the physical and mechanical characterization of Recycled Aggregate Concrete (RAC), produced through a partial-to-total replacement of ordinary aggregates with what have been dubbed Recycled Concrete Aggregates (RCAs). It proposes a theoretical framework for understanding the relationships between RCAs and RCA, and for predicting the resulting behavior of RAC. The book demonstrates that in the case of RAC two additional parameters have to be taken into account than with ordinary aggregates, due to the composite nature and higher porosity of RCAs. By extending Abrams’ Law for Recycled Aggregate Concrete, it represents a first step in the formulation of a general model for predicting the properties of RAC. The theoretical approach presented here addresses an important gap in the literature and is expected to stimulate new research on the use of this more sustainable form of concrete in structural applications.Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053Building materialsMechanicsMechanics, AppliedStructural materialsPhysicsBuilding Materialshttps://scigraph.springernature.com/ontologies/product-market-codes/T23047Solid Mechanicshttps://scigraph.springernature.com/ontologies/product-market-codes/T15010Structural Materialshttps://scigraph.springernature.com/ontologies/product-market-codes/Z11000Numerical and Computational Physics, Simulationhttps://scigraph.springernature.com/ontologies/product-market-codes/P19021Building materials.Mechanics.Mechanics, Applied.Structural materials.Physics.Building Materials.Solid Mechanics.Structural Materials.Numerical and Computational Physics, Simulation.620.13Pepe Marcoauthttp://id.loc.gov/vocabulary/relators/aut1062540MiAaPQMiAaPQMiAaPQBOOK9910299675603321A Conceptual Model for Designing Recycled Aggregate Concrete for Structural Applications2526416UNINA