03266nam 2200589 a 450 991078976700332120211105143149.01-283-23848-997866132384810-12-387823-3(CKB)2670000000112896(EBL)741334(OCoLC)747409504(SSID)ssj0000533740(PQKBManifestationID)11324475(PQKBTitleCode)TC0000533740(PQKBWorkID)10504133(PQKB)11632556(Au-PeEL)EBL741334(CaPaEBR)ebr10496428(CaONFJC)MIL323848(MiAaPQ)EBC741334(EXLCZ)99267000000011289620110415d2012 uy 0engur|n|---|||||txtccrAdvanced topics in forensic DNA typing methodology /John M. ButlerAmsterdam ;Boston :Academic Press,2012.© 20121 online resource (699 pages)Description based upon print version of record.0-12-374513-6 Sample collection, storage, and characterization -- DNA extraction methods -- DNA quantitation -- PCR amplification: capabilities and cautions -- Short tandem repeat (STR) loci and kits -- Capillary electrophoresis: principles and instrumentation -- Quality assurance and validation -- DNA databases: uses and issues -- Missing persons and disaster victim identification efforts -- Degraded DNA -- Low-level DNA testing: issues, concerns, and solutions -- Single nucleotide polymorphisms and applications -- Y-chromosome DNA testing -- Mitochondrial DNA analysis -- X-chromosome analysis -- Non-human DNA -- New technologies and automation -- Legal aspects of DNA testing and the scientific expert in court.Intended as a companion to the Fundamentals of Forensic DNA Typing volume published in 2009, Advanced Topics in Forensic DNA Typing: Methodology contains 18 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field and citation to more than 2800 articles and internet resources. The book builds upon the previous two editions of John Butler’s internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. This book provides the most detailed information written to-date on DNA databases, low-level DNA, validation, and numerous other topics including a new chapter on legal aspects of DNA testing to prepare scientists for expert witness testimony. Over half of the content is new compared to previous editions. A forthcoming companion volume will cover interpretation issues.DNA FingerprintingmethodsDNAphysiologyForensic GeneticsmethodsDNA FingerprintingmethodsDNAphysiologyForensic Geneticsmethods614/.1Butler John M(John Marshall),1969-1494988MiAaPQMiAaPQMiAaPQBOOK9910789767003321Advanced topics in forensic dna typing3718917UNINA