03676nam 2200709 a 450 991078895850332120111129080413.01-4511-2453-81-4698-7482-2(CKB)3400000000000422(EBL)2031972(OCoLC)686682029(SSID)ssj0000445972(PQKBManifestationID)12158423(PQKBTitleCode)TC0000445972(PQKBWorkID)10491383(PQKB)10211488(MiAaPQ)EBC2031972(Au-PeEL)EBL2031972(CaPaEBR)ebr10824498(DLC) 2010023843(DLC)9781605474311(EXLCZ)99340000000000042220100607d2011 uy 0engurcnu||||||||txtccrCancer chemotherapy and biotherapy[electronic resource] principles and practice /[edited by] Bruce A. Chabner, Dan L. Longo5th ed.Philadelphia Wolters Kluwer Health/Lippincott Williams & Wilkinsc20111 online resource (836 p.)Description based upon print version of record.1-60547-431-2 Includes bibliographical references and index.section I. Basic principles of cancer treatment -- section II. Cytotoxic agents -- section III. Molecularly targeted therapies -- section IV. Immunologic agents -- section V. Hormonal therapy -- section VI. Supportive care -- section VII. Survivorship."Updated to include the newest drugs and those currently in development, Cancer Chemotherapy and Biotherapy, Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents--their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. Chapters emphasize pharmacology and mechanisms of action at the molecular and cellular levels, followed by clinical activity and toxicity, both acute and delayed. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations. The previous edition was one of "Doody's Core Titles 2009." This edition's introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised"--Provided by publisher.CancerChemotherapyCancerImmunotherapyAntineoplastic agentsBiological response modifiersNeoplasmsdrug therapyAntineoplastic Agentstherapeutic useBiological Productstherapeutic useCancerChemotherapy.CancerImmunotherapy.Antineoplastic agents.Biological response modifiers.Neoplasmsdrug therapyAntineoplastic Agentstherapeutic useBiological Productstherapeutic use616.99/4061Chabner Bruce1463834Longo Dan L(Dan Louis),1949-327601DNLM/DLCDLCDLCBOOK9910788958503321Cancer chemotherapy and biotherapy3673300UNINA