03373nam 2200577 a 450 991078837870332120230801232013.01-62895-125-71-60917-326-0(CKB)3170000000046488(EBL)1810090(SSID)ssj0000601768(PQKBManifestationID)11353314(PQKBTitleCode)TC0000601768(PQKBWorkID)10566124(PQKB)11290299(MiAaPQ)EBC3338258(OCoLC)797845040(MdBmJHUP)muse17437(MiAaPQ)EBC1810090(Au-PeEL)EBL3338258(CaPaEBR)ebr10562029(Au-PeEL)EBL1810090(EXLCZ)99317000000004648820110722d2012 uy 0engur|n|---|||||txtccrThe quest for cortisone[electronic resource] /Thom RookeEast Lansing [Mich.] Michigan State University Pressc20121 online resource (286 p.)Description based upon print version of record.1-61186-033-4 Includes bibliographical references.Contents; Introduction; Chapter 1. Addison and His Disease; Chapter 2. Introducing Dr. Kendall; Chapter 3. Life After the Thyroid; Chapter 4. Introducing Dr. Hench; Chapter 5. Nice Guys, Saints, Eccentrics, and Geniuses; Chapter 6. 1929 and the Decision to Hunt for Cortisone; Chapter 7. Another Kendall False Start, Another Great Announcement; Chapter 8. Kendall Strikes Out Again; Chapter 9. Kendall Presses On; Chapter 10. Score: Szent-Györgyi-1; Kendall-0; Chapter 11. Transitions and Travels; Chapter 12. War Looms; Chapter 13. Hench Meets KendallChapter 14. World War II and Military Steroid ResearchChapter 15. Plants, Politicians, and More Pessimism; Chapter 16. Good-bye Marker, Hello Sarett; Chapter 17. Hench Returns to Mayo; Chapter 18. Push On? Give Up?; Chapter 19. The Decision to Test Compound E on Rheumatoid Arthritis; Chapter 20. The Amazing Mrs. G.; Chapter 21. A Promising Start; Chapter 22. The Bad and the Ugly; Chapter 23. Progress and Setbacks; Chapter 24. Convincing the Skeptics; Chapter 25. Announcement; Chapter 26. The Prize; Chapter 27. Stockholm; Chapter 28. Aftermath; Chapter 29. TwilightChapter 30. The End of the ShowNotes In 1948, when "Mrs. G.," hospitalized with debilitating rheumatoid arthritis, became the first person to receive a mysterious new compound-cortisone-her physicians were awestruck by her transformation from enervated to energized. After eighteen years of biochemical research, the most intensively hunted biological agent of all time had finally been isolated, identified, synthesized, and put to the test. And it worked. But the discovery of a long-sought "magic bullet" came at an unanticipated cost in the form of strange side effects. This fascinating history recounts the discovery of cortisonCortisoneUnited StatesHistoryCortisoneHistory.610.72/4Rooke Thom W908294MiAaPQMiAaPQMiAaPQBOOK9910788378703321The quest for cortisone3840661UNINA