01429nam0 22003013i 450 VAN008085420160304013352.54488-14-14554-720101130d2009 |0itac50 baitaIT|||| |||||Costruire lo Statola scienza del diritto amministrativo in Italia (1800-1945)Aldo SandulliMilanoGiuffrè2009XVI, 323 p.23 cm.001VAN00088162001 Per la storia del pensiero giuridico modernoUniversità di Firenze, Facoltà di giurisprudenza, Centro di studi per la storia del pensiero giuridico moderno210 MilanoGiuffrè.84Diritto amministrativoItaliaStoria1800-1945VANC031950SGMilanoVANL000284342.450609034Potere esecutivo. Italia. Sec. 19.22SandulliAldo1966- VANV081751313775Giuffrè <editore>VANV109181650ITSOL20230616RICAhttps://www.giuffre.it/49887/INDICE_495733.pdfhttps://www.giuffre.it/49887/INDICE_495733.pdfBIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZAIT-CE0105VAN00VAN0080854BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA00CONS XXI.Db.149 84 00BFG5018 20101130 Costruire lo Stato781650UNICAMPANIA05348nam 2200649 450 991078716400332120200520144314.00-12-802187-X(CKB)3710000000251717(EBL)1811527(SSID)ssj0001374838(PQKBManifestationID)11994564(PQKBTitleCode)TC0001374838(PQKBWorkID)11326497(PQKB)10402985(Au-PeEL)EBL1811527(CaPaEBR)ebr10950298(CaONFJC)MIL649667(OCoLC)899273378(MiAaPQ)EBC1811527(EXLCZ)99371000000025171720141018h20152015 uy 0engur|n|---|||||txtccrDesign and manufacture of pharmaceutical tablets /Reynir EyjolfssonLondon, England :AP,2015.©20151 online resource (68 p.)Description based upon print version of record.0-12-802182-9 1-322-18403-8 Includes bibliographical references at the end of each chapters and index.Cover; Title Page; Copyright Page; Dedication; Contents; Preface; Abbreviations; Chapter One - Introduction; 1.1 - General considerations; 1.2 - Particle sizes; 1.3 - Excipients; 1.3.1 - Ac-Di-Sol SD-711; 1.3.2 - Aerosil 200; 1.3.3 - Avicel PH-102; 1.3.4 - Compactrol; 1.3.5 - Corn starch; 1.3.6 - Di-Tab; 1.3.7 - Eudragit RS PO; 1.3.8 - Magnesium stearate 5712; 1.3.9 - Mannitol 60; 1.3.10 - Methocel K4M Premium; 1.3.11 - Methocel K100M Premium; 1.3.12 - Methocel K100LV Premium; 1.3.13 - Pharmatose 150M; 1.3.14 - Polyplasdone XL-10; 1.3.15 - Povidone; 1.3.16 - Primojel; 1.3.17 - Pruv1.3.18 - Sodium bicarbonate1.3.19 - Starch 1500; 1.3.20 - Stearic acid 2236; 1.3.21 - Sterotex K; 1.3.22 - Tablettose 80; 1.3.23 - Talc; 1.4 - Equipment; 1.5 - Mixing of pharmaceutical powders; 1.6 - Design of experiments; 1.6.1 - Introduction to statistical design of experiments - the two-level factorial; 1.6.1.1 - Introduction; 1.6.1.2 - Designed experiments; 1.6.1.3 - Basic considerations; 1.6.1.4 - Two-level factorials; 1.6.1.5 - Two-level fractional factorials; 1.6.2 - Response surface methodology (RSM); 1.6.2.1 - Introduction; 1.6.2.2 - RSM and a sieving process variable study1.6.2.3 - RSM investigation of the properties of a three-component tablet formulationReferences; Chapter two - Conventional-Release (CR) Tablets; 2.1 - Low-dose tablet by direct compression (DC); 2.1.1 - Properties of active pharmaceutical ingredient (API); 2.1.2 - Design; 2.1.3 - Manufacturing method; 2.1.4 - Remarks; 2.2 - High-dose tablet by direct compression; 2.2.1 - Properties of active pharmaceutical ingredient; 2.2.2 - Design; 2.2.3 - Manufacturing method; 2.2.4 - Remarks; 2.3 - Low-solubility API, low-dose tablet by wet granulation (WG)2.3.1 - Properties of active pharmaceutical ingredient2.3.2 - Design; 2.3.3 - Manufacturing method; 2.3.4 - Remarks; 2.4 - Soluble API, low-dose tablet by wet granulation; 2.4.1 - Properties of active pharmaceutical ingredient; 2.4.2 - Design; 2.4.3 - Manufacturing method; 2.4.4 - Remarks; 2.5 - Low-solubility API, high-dose tablet by wet granulation; 2.5.1 - Properties of active pharmaceutical ingredient; 2.5.2 - Design; 2.5.3 - Manufacturing method; 2.5.4 - Remarks; 2.6 - Soluble API, high-dose tablet by wet granulation; 2.6.1 - Properties of active pharmaceutical ingredient; 2.6.2 - Design2.6.3 - Manufacturing method2.6.4 - Remarks; References; Chapter three - Slow-Release (SR) Tablets; 3.1 - Slow-release tablet using a lipophilic release control agent; 3.1.1 - Properties of active pharmaceutical ingredient (API); 3.1.2 - Design; 3.1.3 - Manufacturing method; 3.1.4 - Remarks; 3.2 - Slow-release tablet using Eudragit and Methocel as release control agents; 3.2.1 - Properties of active pharmaceutical ingredient; 3.2.2 - Design; 3.2.3 - Manufacturing method; 3.2.4 - Remarks; 3.3 - Slow-release tablet using a mixture of Methocels as release control agent3.3.1 - Properties of active pharmaceutical ingredientDesign and Manufacture of Pharmaceutical Tablets offers real world solutions and outcomes of formulation and processing challenges of pharmaceutical tablets. This book includes numerous practical examples related to actual formulations that have been validated and marketed and covers important data in the areas of stability, dissolution, bioavailibity and processing. It provides important background and theoretical information on design and manufacturing and includes a full section dedicated to design experimental methodology and statistics. In addition, this book offers a a general discussDrugsDosage formsPharmaceutical industryTablets (Medicine)DrugsDosage forms.Pharmaceutical industry.Tablets (Medicine)615.1Eyjolfsson Reynir1478141MiAaPQMiAaPQMiAaPQBOOK9910787164003321Design and manufacture of pharmaceutical tablets3693753UNINA