03225oam 2200613I 450 991078683610332120170821193846.00-429-07396-81-4665-9271-010.1201/b16839 (CKB)3710000000108098(EBL)1550642(SSID)ssj0001197071(PQKBManifestationID)11731055(PQKBTitleCode)TC0001197071(PQKBWorkID)11176671(PQKB)11138200(OCoLC)879550869(MiAaPQ)EBC1550642(OCoLC)1350746522(OCoLC-P)1350746522(CaSebORM)9781466592698(EXLCZ)99371000000010809820180331h20142014 uy 0engur|n|---|||||txtccrSynthetic gene network modeling, analysis, and robust design methods /Bor-Sen Chen, Laboratory of Control and Systems Biology, Department of Electrical Engineering, National Tsing Hua University, Hsinchu, Taiwan and Yu-Chao Wang, Institute [First edition].Boca Raton :CRC Press/Taylor & Francis Group,[2014]©20141 online resource (216 p.)Description based upon print version of record.1-306-86807-6 1-4665-9269-9 Includes bibliographical references and index.Front Cover; Preface; Contents; Chapter 1: General Introduction; Chapter 2: Mathematical Models and Design Specifications in Synthetic Gene Networks; Chapter 3: Robust Synthetic Biology Designs based on System Dynamic Models; Chapter 4: Robust Synthetic Biology Designs based on Network Evolutionary Methods; Chapter 5: Construction of Promoter and Promoter-RBS Libraries for Synthesis of Gene Networks; Chapter 6: Robust Synthetic Gene Network Designs based on Library-search Method; Chapter 7: Robust Design of Synthetic Biological Filter and Transistor based on Promoter-RBS LibrariesChapter 8: Communication and Synchronization of a Population of Coupled Synthetic Gene NetworksColor Plate Section; Back CoverThis book develops a rational design and systematic approach to construct a gene network with desired behaviors. In order to achieve this goal, the registry of standard biological parts and experimental techniques are introduced at first. Then these biological components are characterized by a standard modeling method and collected in the component libraries, which can be efficiently reused in engineering synthetic gene networks. Based on the system theory, some design specifications are provided to engineer the synthetic gene networks to robustly track the desired trajectory by employing tGene regulatory networksGenetic engineeringGene regulatory networks.Genetic engineering.576.5Chen Bor-Sen943906Wang Yu-Chao1981-FlBoTFGFlBoTFGBOOK9910786836103321Synthetic gene network3682197UNINA