03247oam 2200685I 450 991078384680332120230422044313.00-429-17691-01-4822-9821-X1-280-07171-097866100717150-203-30365-210.1201/9781482298215 (CKB)1000000000253714(EBL)181540(OCoLC)437084398(SSID)ssj0000284179(PQKBManifestationID)11256034(PQKBTitleCode)TC0000284179(PQKBWorkID)10261017(PQKB)11112240(OCoLC)647436282(MiAaPQ)EBC181540(Au-PeEL)EBL181540(CaPaEBR)ebr10099677(CaONFJC)MIL7171(OCoLC)1000433960(EXLCZ)99100000000025371420180706d1999 uy 0engur|n|---|||||txtccrSignalling pathways in apoptosis /edited by Dianne Watters and Martin LavinAmsterdam :Harwood Academic,1999.1 online resource (338 p.)Modern genetics,1056-4497 ;v. 5Description based upon print version of record.0-203-35369-2 90-5702-392-X Includes bibliographical references and index.Book Cover; Title; Contents; Preface to the Series; Preface; Contributors; Overview: A Matter of Life and Death; The Death Receptors; The Role of Sphingolipids in Stress Responses and Apoptosis in Eukaryotes; Radiation Response Pathways and Apoptosis; Kinase Cascades and Apoptosis; Protein Kinase C Isoenzymes: Evidence for Selectivity in the Regulation of Apoptosis; Apoptosis in Drosophila; Baculoviral Lessons in Apoptosis; The Mitochondrion: Decisive for Cell Death Control?; Caspases and the Commitment to Death; Caspases: The Molecular Effectors of Apoptosis; Killer CellsDeliverers of Exogenous Death ProteasesSubstrates of Cell Death Proteases and their Role in Apoptosis; IndexApoptosis, or programmed cell death, is a necessary process by which a cell may die without adversely affecting its environment. It plays a crucial role in normal development, and in the body's defence mechanisms against disease. Too much cell death is destructive, leading to neurodegenerative diseases and impaired development. Conversely, too little cell death can lead to an increased susceptibility to cancer and sustained viral infection. Apoptosis is a matter of balanceDramatic progress has been made in the study of apoptosis over the past decade. One of the most rapidly expanding knowlModern genetics ;v. 5.ApoptosisCellular signal transductionApoptosis.Cellular signal transduction.571.936Lavin Martin1943-1543903Watters Dianne1952-1543904MiAaPQMiAaPQMiAaPQBOOK9910783846803321Signalling pathways in apoptosis3797658UNINA