04044nam 22008414a 450 991078378360332120230828231159.01-84769-925-11-280-50168-597866105016871-85359-863-110.21832/9781853598630(CKB)1000000000245143(EBL)255752(OCoLC)475970776(SSID)ssj0000261884(PQKBManifestationID)12049155(PQKBTitleCode)TC0000261884(PQKBWorkID)10268759(PQKB)10134337(SSID)ssj0000366953(PQKBManifestationID)12101746(PQKBTitleCode)TC0000366953(PQKBWorkID)10417109(PQKB)11634243(MiAaPQ)EBC255752(DE-B1597)491315(OCoLC)1046618799(DE-B1597)9781853598630(Au-PeEL)EBL255752(CaPaEBR)ebr10120628(CaONFJC)MIL50168(EXLCZ)99100000000024514320050725d2006 uy 0engur|n|---|||||txtccrTravel notes from the new literacy studies[electronic resource] instances of practice /edited by Kate Pahl and Jennifer RowsellClevedon [England] ;Buffalo Multilingual Mattersc20061 online resource (278 p.)New perspectives on language and educationDescription based upon print version of record.1-85359-861-5 1-85359-862-3 Includes bibliographical references and index.Global, local/public, private: young children's engagement in digital literacy --Practices in the home /Jackie Marsh --Ned and Kevin: an online discussion that challenges the 'not-yet adult' cultural model /Donna Alvermann --Escaping to the borderlands: an exploration of the Internet as a cultural space for teenaged Wiccan girls /Julia Davies --Weblog worlds and constructions of effective and powerful writing: cross with care, and only where signs permit /Michele Knobel and Colin Lankshear --Critical literacy across continents /Hilary Janks and Barbara Comber --An eye on the text and an eye on the future: multimodal literacy in three Gauteng families /Pippa Stein and Lynne Slominsky --Crossing the margins: recontextualisation, literacy and semiotic power? /Cathy Kell --From boardroom to classroom: tracing a globalised discourse on thinking through Internet texts and teaching practice /Sue Nichols --Corporate crossings: tracing textual crossings /Jennifer Rowsell --So, what about multimodal numeracies? /Brian Street and Dave Baker --Transformative pedagogy: teachers creating a literacy of fusion /Elaine Millard.This book joins two important fields, that of literacy and multimodality, with a focus on local and global literacies. Chapters include work on media, popular culture and literacy, weblogs, global and local crossings, in and out of educational settings in such locations as the US, the UK, South Africa, Australia and Canada.New perspectives on language and education.LiteracyTechnological literacyGlobalizationNew Literacy Studies.South Africa.South Australia.literacy practices.literacy studies.multimodal literacies.multimodality.Literacy.Technological literacy.Globalization.302.2/244Pahl Kate1479171Rowsell Jennifer1969-951082MiAaPQMiAaPQMiAaPQBOOK9910783783603321Travel notes from the new literacy studies3695162UNINA06361nam 22008895 450 991029826790332120220727194510.03-319-20825-X10.1007/978-3-319-20825-1(CKB)3710000000479184(EBL)4178347(SSID)ssj0001583189(PQKBManifestationID)16258188(PQKBTitleCode)TC0001583189(PQKBWorkID)14861988(PQKB)10842333(DE-He213)978-3-319-20825-1(MiAaPQ)EBC4178347(PPN)190532556(EXLCZ)99371000000047918420150925d2015 u| 0engur|n#---|||||txtccrEndocannabinoids /edited by Roger G. Pertwee1st ed. 2015.Cham :Springer International Publishing :Imprint: Springer,2015.1 online resource (477 p.)Handbook of Experimental Pharmacology,0171-2004 ;231Description based upon print version of record.3-319-20824-1 Includes bibliographical references at the end of each chapters and index.Preface; The Endocannabinoid System: A Look Back and Ahead; Contents; Endocannabinoids and Their Pharmacological Actions; 1 Introduction; 2 Evidence That Certain Endogenous Compounds Target Cannabinoid Receptors Orthosterically; 2.1 Evidence from Binding Assays; 2.2 Evidence from Two Functional Bioassays; 2.2.1 [35S]GTPgammaS Binding Assay; 2.2.2 Cyclic AMP Assay; 3 Non-Cannabinoid Receptors and Channels Targeted by Endogenous Cannabinoid Receptor Ligands at Submicromolar Concentrations; 3.1 Non-Cannabinoid G Protein-Coupled Receptors; 3.1.1 GPR55; 3.2 Ligand-Gated Ion Channels3.2.1 5-HT3 Receptors3.2.2 Nicotinic Acetylcholine Receptors; 3.2.3 Glycine Receptors; 3.2.4 Ionotropic Glutamate NMDA Receptors; 3.3 Transient Receptor Potential Channels; 3.3.1 TRPV1; 3.3.2 TRPM8 Channels; 3.4 Voltage-Gated Calcium Channels; 3.4.1 T-Type Cav3 Calcium Channels; 3.5 Potassium Channels; 3.5.1 ATP-Sensitive Inward Rectifier KATP Channels of the 2TM Domain Family; 3.5.2 Voltage-Gated Kv and KCa Channels of the 6TM Domain Family; 4 Allosteric Endocannabinoids; 5 Conclusions; References; Biosynthesis and Fate of Endocannabinoids1 Endocannabinoids and Endocannabinoid-Like Compounds2 Biosynthesis of the Endocannabinoids; 3 Uptake of the Endocannabinoids: Proposed Mechanisms; 4 Degradation of the Endocannabinoids; 4.1 FAAH and NAAA; 4.2 MGL, ABHD6 and ABHD12; 5 Conclusions; References; Distribution of the Endocannabinoid System in the Central Nervous System; 1 Introduction; 1.1 Overview; 1.2 Cells Expressing Components of the ECS; 1.3 Subcellular Localization of CB1 Cannabinoid Receptors; 2 Retina; 2.1 Receptors; 2.2 Synthetic Enzymes; 2.3 Degradative Enzymes; 3 Cerebral Cortex; 3.1 Neocortex; 3.1.1 Receptors3.1.2 Synthetic Enzymes3.1.3 Degradative Enzymes; 3.2 Olfactory Areas (Olfactory Bulb, Piriform Cortex, Associated Regions); 3.2.1 Receptors; 3.2.2 Synthetic Enzymes; 3.2.3 Degradative Enzymes; 3.3 Hippocampal Formation; 3.3.1 Receptors; 3.3.2 Synthetic Enzymes; 3.3.3 Degradative Enzymes; 3.4 Cortical Subplate (Other Amygdala Nuclei); 3.4.1 Receptors; 3.4.2 Synthetic Enzymes; 3.4.3 Degradative Enzymes; 4 Subcortical Nuclei (Striatum, Basal Ganglia); 4.1 Striatum (Dorsal, Caudate); 4.1.1 Receptors; 4.1.2 Synthetic Enzymes; 4.1.3 Degradative Enzymes; 4.2 Striatum (Ventral, Accumbens)4.2.1 Receptors4.2.2 Synthetic Enzymes; 4.2.3 Degradative Enzymes; 4.3 Striatum Medial (Lateral Septum, Septohippocampal, etc.); 4.3.1 Receptors; 4.3.2 Synthetic Enzymes; 4.3.3 Degradative Enzymes; 4.4 Striatum Caudal (Striatum-like Amygdala Nuclei, Central Amygdala, Bed Nucleus, Medial Amygdala, Etc.); 4.4.1 Receptors; 5 Cerebellum and Associated Nuclei; 5.1 Cerebellar Cortex; 5.1.1 Receptors; 5.1.2 Synthetic Enzymes; 5.1.3 Degradative Enzymes; 5.2 Deep Cerebellar Nuclei (Fastigial, Interpos, Dentate Nucleus); 5.2.1 Receptors; 5.2.2 Synthetic Enzymes; 5.2.3 Degradative Enzymes; 6 Brainstem6.1 DiencephalonThere is currently considerable interest in the development of medicines that would enhance endocannabinoid-induced “autoprotection”, for example through inhibition of endocannabinoid metabolizing enzymes or cellular uptake processes or that would oppose endocannabinoid-induced “autoimpairment”. This volume describes the physiology, pathophysiology and pharmacology of the endocannabinoid system and potential strategies for targeting this system in the clinic.Handbook of Experimental PharmacologyPharmacologyCytologyNeurosciencesPsychopharmacologyImmunologyCytokinesGrowth factorsPharmacology/Toxicologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B21007Cell Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L16008Neuroscienceshttps://scigraph.springernature.com/ontologies/product-market-codes/B18006Psychopharmacologyhttps://scigraph.springernature.com/ontologies/product-market-codes/H53010Immunologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B14000Cytokines and Growth Factorshttps://scigraph.springernature.com/ontologies/product-market-codes/L14120Pharmacology.Cytology.Neurosciences.Psychopharmacology.Immunology.Cytokines.Growth factors.Pharmacology/Toxicology.Cell Biology.Neurosciences.Psychopharmacology.Immunology.Cytokines and Growth Factors.615.7827Pertwee R. G(Roger G.),edthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910298267903321Endocannabinoids1383799UNINA