04510nam 2201009z- 450 991058021390332120231214133523.0(CKB)5690000000011949(oapen)https://directory.doabooks.org/handle/20.500.12854/87533(EXLCZ)99569000000001194920202207d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierNeurotransmitter-Related Molecular Modeling StudiesBaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (188 p.)3-0365-4277-9 3-0365-4278-7 This book focuses of the neurotransmission phenomenon. By definition, neurotransmitters are chemicals that enable communication, i.e., the flow of nerve impulses between nerve cells or between nerve cells and muscles and glands. Recently, one can distinguish excitatory and inhibitory mediators, both of which are endo–exogenous compounds that control the function of the whole organism. From a chemical point of view, neurotransmitters belong to many different structural groups, such as amino acids (such as glycine), peptides (such as substance P, somatostatin), monoamines (such as noradrenaline or dopamine), purine derivatives (such as adenosine), gases (such as nitrogen, NO, carbon monoxide CO), and acetylcholine. From a medical point of view, disturbances in the concentration of neurotransmitters in the body result in the occurrence of mental disorders and diseases (such as depression, schizophrenia, Parkinson’s disease) and contribute to the occurrence of dementia (including Alzheimer’s disease), among other diseases. However, the problem is much wider. These disorders can lead to a number of cardiovascular diseases and can lead to the development of vascular diseases of the brain as well as in many other organs. Therefore, pharmacological intervention is a therapy that tries to interfere with regulatory processes year after year. Such treatments improve survival, reduce the frequency of readmission, and improve patients' quality of life.Research & information: generalbicsscChemistrybicsscwhite matter hyperintensitiesdysautonomiagenetic polymorphismsdementialevodoparenin-angiotensin systemorthostatic hypotensionreserpine-induced fibromyalgia modelvortioxetineropiniroleserotonin and dopamine in fibromyalgiamousedopamineacetylcholineglutamateBDNFserotoninneurotransmittersstatinsneurodegenerative diseasesstrokedepressionandrogenetic alopecia3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitorsmixed dyslipidemiarisk factorshalogenated pyrazolinesmonoamine oxidase inhibitorskineticsreversibilitymolecular dynamicsguanylate cyclase (GC)chronic heart failure (CHF)pulmonary arterial hypertension (PAH)tiagabinecardiac voltage-gated ion channelsmolecular modelingECG studySGLT2isodium-glucose cotransporter 2 inhibitorsneuroprotectionatheroprotectionmTORtype 2 diabetes mellituscognitive impairmentinflammationoxidative stressantibioticsneurotoxicityadverse drug reactionneurotransmission5-HT receptorsgastrointestinal tractResearch & information: generalChemistryNowaczyk Alicjaedt1332311Grześk GrzegorzedtNowaczyk AlicjaothGrześk GrzegorzothBOOK9910580213903321Neurotransmitter-Related Molecular Modeling Studies3040814UNINA05247nam 2201057Ia 450 991078338980332120230617012957.01-282-35730-197866123573050-520-93063-01-4175-4515-110.1525/9780520930636(CKB)1000000000024214(EBL)224706(OCoLC)228113312(SSID)ssj0000152049(PQKBManifestationID)11147129(PQKBTitleCode)TC0000152049(PQKBWorkID)10322325(PQKB)10418259(StDuBDS)EDZ0000055770(OCoLC)56713888(MdBmJHUP)muse30404(MiAaPQ)EBC224706(DE-B1597)520506(DE-B1597)9780520930636(Au-PeEL)EBL224706(CaPaEBR)ebr10068609(CaONFJC)MIL235730(EXLCZ)99100000000002421420040705d2004 uy 0engurnn#---|u||utxtccrExperimental approaches to conservation biology[electronic resource] /edited by Malcolm S. Gordon and Soraya M. BartolBerkeley, Calif. ;London University of California Press20041 online resource (360 p.)Formerly CIP.Uk0-520-24024-3 Includes bibliographical references and index.Front matter --Contents --Acknowledgments --Contributors --1. Experimental Biology in Conservation Science --2. Overview --3. Contributions of Ex Situ Propagation and Molecular Genetics to Conservation of Hawaiian Tree Snails --4. Multiple Causes for Declining Amphibian Populations --5. Energetics of Leatherback Sea Turtles --6. Experimental Strategies for the Recovery of Depleted Populations of West Indian Rock Iguanas --7. Endocrinology and the Conservation of New Zealand Birds --8. Conservation of Australian Arid-Zone Marsupials --9. The Population Decline of Steller Sea Lions --10. Overview --11. Tipping the Balance in the Restoration of Native Plants --12. Using Natural Experiments in the Study of Alien Tree Invasions --13. Biological Control in Support of Conservation --14. Overview --15. The Army and the Desert Tortoise --16. Integrating Experimental Research with the Needs of Natural-Resource and Land Managers --17. Making Wildlife Research More Meaningful by Prioritizing Science, Linking Disciplines, and Building Capacity --18. African National Parks under Challenge --Systematic Index --Subject IndexWe are living in the early stages of a looming worldwide extinction crisis. Abundant evidence shows that the current rate of species extinctions is nearing its highest level since the asteroid collision 65 million years ago, and that humans are largely responsible. This book addresses the urgent need to understand and find solutions to this crisis. Written by an international team of contributors who are among the best-known and most active experimental biologists working in the field of conservation biology today, it provides a unique approach by focusing on individual species rather than whole plant and animal communities. Emphasizing throughout how conservation biology can benefit from an experimental approach, the book looks at a wide range of terrestrial and aquatic species-from giant pandas and tree snails to sea turtles and Steller sea lions-and demonstrates what can be done both to preserve rare species and to combat invasive organisms. Finally, contributors show how we can bridge the gap between policy makers and research scientists in order to develop lasting solutions to these problems.Conservation biologyBiology, Experimentalamphibians.animal populations.australia.biodiversity.biology.conservation.desert tortoise.ecology.ecosystem.endangered animals.environment.environmentalism.extinction.grassland.hawaiian tree snails.healthy ocean.invasive species.leatherneck sea turtles.marine animals.marine biology.marsupials.national parks.native plants.natural sciences.new zealand.nonfiction.ocean animals.ocean.oceanography.rock iguanas.science.sea lions.sea.Conservation biology.Biology, Experimental.639.9Gordon Malcolm S511909Bartol Soraya M.1970-1463399MiAaPQMiAaPQMiAaPQBOOK9910783389803321Experimental approaches to conservation biology3672679UNINA