05385nam 2200637Ia 450 991078081600332120190510224449.01-282-38165-297866123816520-08-096516-4(CKB)2550000000000897(EBL)477371(OCoLC)742296779(SSID)ssj0000341866(PQKBManifestationID)12134380(PQKBTitleCode)TC0000341866(PQKBWorkID)10396267(PQKB)10449130(MiAaPQ)EBC477371(PPN)182566870(EXLCZ)99255000000000089719891018d2009 uy 0engur|n|---|||||txtccrProgress in heterocyclic chemistryVolume 21Critical review of the 2006 literature preceded by two chapters on current heterocyclic topics[electronic resource] /editors, Gordon W. Gribble and John A. JouleOxford ;New York Pergamon Press20091 online resource (573 p.)Progress in heterocyclic chemistry ;21Description based upon print version of record.0-08-096515-6 Includes bibliographical references and index.Front Cover; Progress in Heterocyclic Chemistry; Copyright Page; Contents; Foreword; Chapter 1 Biocatalytic Approaches to Chiral Heterocycles; 1.1 Introduction; 1.2 Enzyme classes discussed; 1.3 Three-membered ring systems; 1.4. Four-membered ring systems; 1.5 Five-membered ring systems; 1.6 Six-membered ring systems; 1.7 Seven-membered and larger ring systems; 1.8 Conclusion; 1.9 References; Chapter 2 Ring-Expanded ('fat') Purines and their Nucleoside/ Nucleotide Analogues as Broad-Spectrum Therapeutics; 2.1 Introduction2.2 Significance of 'fat' purines and their nucleoside/nucleotide analogues2.3 Chemistry; 2.4 Biochemical and biophysical chemistry; 2.5 Biological activity; 2.6 Conclusion; 2.7 Acknowledgments; 2.8 References; Chapter 3 Three-Membered Ring Systems; 3.1 Introduction; 3.2 Epoxides; 3.3 Aziridines; 3.4 References; Chapter 4 Four-Membered Ring Systems; 4.1 Introduction; 4.2 Azetidines, azetines, and related systems; 4.3 Monocyclic 2-azetidinones (ß-lactams); 4.4 Fused and spirocyclic ß-lactams; 4.5 Oxetanes, dioxetanes, oxetanediones and 2-oxetanones ( ß-lactones)4.6 Thietanes, ß-sultams, and related systems4.7 Silicon and phosphorus heterocycles. Miscellaneous; 4.8 References; Chapter 5.1 Five-Membered Ring Systems: Thiophenes and Se/Te Analogues; 5.1.1 Introduction; 5.1.2 Thiophene ring synthesis; 5.1.3 Reactions of thiophenes; 5.1.4 Non-polymeric thiophene organic materials; 5.1.5 Thiophene oligomers and polymers; 5.1.6 Thiophene derivatives in medicinal chemistry; 5.1.7 Selenophenes and tellurophenes; 5.1.8 References; Chapter 5.2 Five-Membered Ring Systems: Pyrroles and Benzo Analogs; 5.2.1 Introduction; 5.2.2 Synthesis of pyrroles5.2.3 Reactions of pyrroles5.2.4 Pyrrole natural products and materials; 5.2.5 Synthesis of indoles; 5.2.6 Reactions of indoles; 5.2.7 Indole natural products; 5.2.8 Oxindoles and spirooxindoles; 5.2.9 Carbazoles; 5.2.10 Azaindoles and carbolines; 5.2.11 Bioorganic chemistry; 5.2.12 References; Chapter 5.3 Five-Membered Ring Systems: Furans and Benzofurans; 5.3.1 Introduction; 5.3.2 Reactions; 5.3.3 Synthesis; 5.3.4 References; Chapter 5.4 Five Membered Ring Systems: With More than One N Atom; 5.4.1 Introduction; 5.4.2 Pyrazoles and ring-fused derivatives5.4.3 Imidazoles and ring-fused derivatives5.4.4 1,2,3-Triazoles and ring-fused derivatives; 5.4.5 1,2,4-Triazoles and ring-fused derivatives; 5.4.6 Tetrazoles and ring-fused derivatives; 5.4.7 References; Chapter 5.5 Five-Membered Ring Systems: With N and S (Se) Atoms; 5.5.1 Introduction; 5.5.2 Thiazoles; 5.5.3 Isothiazoles; 5.5.4 Thiadiazoles and selenodiazoles; 5.5.5 1,3-Selenazoles, 1,3-selenadolidines and 1,3-tellurazoles; 5.5.6 References; Chapter 5.6 Five-Membered Ring Systems: With O & S (Se, Te) Atoms; 5.6.1 1,3-Dioxoles and dioxolanes; 5.6.2 1,3-Dithioles and dithiolanes5.6.3 1,3-Oxathioles and oxathiolanesProgress in Heterocyclic Chemistry (PHC) is an annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC). Volumes in the series contain both highlights of the previous year's literature on heterocyclic chemistry and articles on emerging topics of particular interest to heterocyclic chemists. The chapters in Volume 21 constitute a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2008. Additional articles in this volume review ""Biocatalytic approaches to chiral heterocycles"" and ""Ring-eProgress in Heterocyclic ChemistryHeterocyclic chemistryHeterocyclic compoundsHeterocyclic chemistry.Heterocyclic compounds.547.59Gribble Gordon W93007Joule J. A(John Arthur)91644MiAaPQMiAaPQMiAaPQBOOK9910780816003321Progress in heterocyclic chemistry3825671UNINA