04031nam 22007332 450 991077958980332120151005020621.01-107-23773-41-107-30590-X1-107-30692-21-107-30912-31-107-30183-11-107-31467-41-139-38166-01-107-31247-71-299-00912-3(CKB)2550000001003957(EBL)1113106(OCoLC)827210301(SSID)ssj0000827224(PQKBManifestationID)11519023(PQKBTitleCode)TC0000827224(PQKBWorkID)10830876(PQKB)10441126(UkCbUP)CR9781139381666(MiAaPQ)EBC1113106(Au-PeEL)EBL1113106(CaPaEBR)ebr10649582(CaONFJC)MIL432162(PPN)261277278(EXLCZ)99255000000100395720141103d2013|||| uy| 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierPreventing and treating missing data in longitudinal clinical trials a practical guide /Craig H. Mallinckrodt[electronic resource]Cambridge :Cambridge University Press,2013.1 online resource (xviii, 165 pages) digital, PDF file(s)Practical guides to biostatistics and epidemiologyTitle from publisher's bibliographic system (viewed on 05 Oct 2015).1-107-03138-9 1-107-67915-X Includes bibliographical references and index.Machine generated contents note: Part I. Background and Setting: 1. Why missing data matter; 2. Missing data mechanisms; 3. Estimands; Part II. Preventing Missing Data: 4. Trial design considerations; 5. Trial conduct considerations; Part III. Analytic Considerations: 6. Methods of estimation; 7. Models and modeling considerations; 8. Methods of dealing with missing data; Part IV. Analyses and the Analytic Road Map: 9. Analyses of incomplete data; 10. MNAR analyses; 11. Choosing primary estimands and analyses; 12. The analytic road map; 13. Analyzing incomplete categorical data; 14. Example; 15. Putting principles into practice.Recent decades have brought advances in statistical theory for missing data, which, combined with advances in computing ability, have allowed implementation of a wide array of analyses. In fact, so many methods are available that it can be difficult to ascertain when to use which method. This book focuses on the prevention and treatment of missing data in longitudinal clinical trials. Based on his extensive experience with missing data, the author offers advice on choosing analysis methods and on ways to prevent missing data through appropriate trial design and conduct. He offers a practical guide to key principles and explains analytic methods for the non-statistician using limited statistical notation and jargon. The book's goal is to present a comprehensive strategy for preventing and treating missing data, and to make available the programs used to conduct the analyses of the example dataset.Practical guides to biostatistics and epidemiology.Preventing & Treating Missing Data in Longitudinal Clinical TrialsClinical trialsLongitudinal studiesMedical sciencesStatistical methodsRegression analysisData processingClinical trialsMedical sciencesStatistical methods.Regression analysisData processing.610.72/4MED090000bisacshMallinckrodt Craig H.1958-1548067UkCbUPUkCbUPBOOK9910779589803321Preventing and treating missing data in longitudinal clinical trials3804868UNINA03298nam 22006014a 450 991078017350332120230330224051.01-280-82895-197866108289510-85199-710-4(CKB)111056486821648(EBL)293844(OCoLC)476055680(SSID)ssj0000100510(PQKBManifestationID)11124496(PQKBTitleCode)TC0000100510(PQKBWorkID)10036979(PQKB)11630455(MiAaPQ)EBC293844(Au-PeEL)EBL293844(CaPaEBR)ebr10058882(EXLCZ)9911105648682164819991018h20002000 uy 0engur|n|---|||||txtrdacontentcrdamediacrrdacarrierAgriculture and intellectual property rights economic, institutional, and implementation issues in biotechnology /editors, V. Santaniello [et al.]Wallingford, Oxon, UK ;New York :CABI Pub.,2000.©20001 online resource (ix, 259 pages)Description based upon print version of record.0-85199-457-1 Includes bibliographical references and index.Contents; Contributors; Acknowledgements; Introduction; 1 Patent and Other Private Legal Rights for Biotechnology Inventions (Intellectual Property Rights - IPR); 2 Intellectual Property Rights of Plant Varieties and of Biotechnology in the European Union; 3 Intellectual Property Rights under the Convention on Biological Diversity; 4 An Economic Approach to Identifying an 'Effective sui generis System' for Plant Variety Protection Under TRIPs*; 5 Recent Intellectual Property Rights Controversies and Issues at the CGIAR; 6 Economics of Intellectual Property Rights for Agricultural Technology7 The Market Value of Farmers' Rights; 8 International Crop Breeding in a World of Proprietary Technology; 9 Knowledge Management and the Economics of Agricultural Biotechnology; 10 Comparing Allocation of Resources in Public and Private Research*; 11 Biotechnology Inventions: What Can We Learn from Patents?; 12 Biotechnology Inventions: Patent Data Evidence; 13 Property Rights and Regulations for Transgenic Crops in North America*; 14 Intellectual Property Rights, Canola and Public Research in Canada; IndexPlant breeding patents, the ownership of biological innovation and associated intellectual property rights (IPR) are the subject of increased attention worldwide. Particularly relevant to the field of biotechnology, this book presents the perspectives of policy-makers and economists on such issues.Germplasm resources, PlantCongressesAgricultural biotechnologyCongressesIntellectual propertyCongressesGermplasm resources, PlantAgricultural biotechnologyIntellectual property631.5/23Santaniello V89651MiAaPQMiAaPQMiAaPQBOOK9910780173503321Agriculture and intellectual property rights3858514UNINA