04698nam 2200601Ia 450 991077952230332120230721010802.01-60876-591-1(CKB)2550000001041296(EBL)3018375(SSID)ssj0000852898(PQKBManifestationID)12350749(PQKBTitleCode)TC0000852898(PQKBWorkID)10864317(PQKB)11588273(MiAaPQ)EBC3018375(Au-PeEL)EBL3018375(CaPaEBR)ebr10660236(OCoLC)872684169(EXLCZ)99255000000104129620130318d2009 uy 0engur|n|---|||||txtccrHeart transplantation[electronic resource] indications and contradictions, procedures and complications /Catherine T. Fleming, editorNew York Nova Biomedical Booksc20091 online resource (313 p.)Cardiology research and clinical developments seriesDescription based upon print version of record.1-60741-228-4 Includes bibliographical references and index.""Heart Transplantation: Indications and Contradictions, Procedures and Complications""; ""Contents""; ""Preface""; ""Management of Tricuspid Regurgitation After Cardiac Transplantation""; ""Abstract ""; ""Introduction ""; ""Pathophysiology of Tricuspid Valve Regurgitation Following Cardiac Transplantation ""; ""Management of Refractory Tricuspid Regurgitation ""; ""Recent Experience with Repairs and Replacements ""; ""Repair or Replacement? ""; ""Preventing Post-Transplant TR ""; ""Conclusion ""; ""References """"Virtual Histology Intravascular Ultrasound in Coronary Allograft Vasculopathy""""References""; ""Gene Therapy for Prevention of Acute and Chronic Cardiac Rejection""; ""Abstract ""; ""1. Introduction ""; "" 2. Antisense Cyclin-Dependent Kinase (cdk) 2 Kinase ODN ""; ""3. Antisense Proliferating-Cell Nuclear Antigen (PCNA) ODN ""; ""4. Antisense Bcl-x ODN""; ""5. E2F Decoy ""; ""6. NF-kB Decoy ""; ""7. Summary ""; ""Acknowledgement""; ""References ""; ""Prevention of Heart Allograft Rejection by Immunotherapy with Ex Vivo-Expanded Foxp3+CD4+CD25+ Natural Regulatory T Cells""; ""Abstract""""Introduction """"Overview of Foxp3+CD4+CD25+ nTreg Cells ""; ""Foxp3+CD4+CD25+ Treg Cells and Allograft Rejection ""; ""Foxp3+CD4+CD25+ Treg Cells and Allograft Tolerance ""; "" Rationale for Immunotherapy with Foxp3+CD4+CD25+ nTreg Cells ""; ""Strategies and Procedures for Ex Vivo Expansion of CD4+CD25+ nTreg Cells ""; ""Dynamics of Foxp3 Expression during Ex Vivo Expansion ""; ""Suppressive Activity in MLR Assays ""; ""Engraftment, Trafficking and Homing after Adoptive Transfer ""; "" In Vivo Suppression and Allograft Survival ""; ""Determinants of in Vivo Therapeutic Efficacy""""Issues Regarding CD8+CD25+ nTreg Cells """" Generation and Application of Foxp3+CD4+CD25+ iTreg Cells ""; ""Challenges to Clinical Application ""; ""Conclusion ""; ""References""; ""Addressing the Shortage of Donor Cardiac Allografts - Use of Marginal Grafts""; ""Abstract""; ""Introduction""; ""Strategies to Improve Donor Organ Utilization""; ""Expanding the Use of Marginal Donor Organs""; "" Use of Marginal Cardiac Allografts for Heterotopic Transplantation ""; ""Use of Long Ischemic Time Organs as Marginal Allografts ""; ""Primary Graft Failure as a Consequence of Marginal Graft Use""""Older Donors and Cardiac Arrest Donors """"Continuous Perfusion of Donor Organs ""; ""Conclusion ""; ""References ""; ""Dendritic Cell Modulation for Therapeutic Immunoregulation in Heart Transplantation""; ""Abstract""; ""Introduction ""; ""Direct and Indirect Allorecognition ""; "" Dendritic Cell Subsets and Dendritic Cell Maturation in Organ Transplantation ""; ""Circulating Dendritic Cells in Human Organ Transplantation ""; ""Therapeutic Strategies Based on Genetically Modified Dendritic Cells ""; ""Therapeutic Modulation of Dendritic Cell Chemoattraction""""Generation of Regulatory Dendritics Cells ""Cardiology Research and Clinical DevelopmentsHeartTransplantationHeartSurgeryHeartTransplantation.HeartSurgery.617.4120592Fleming Catherine T1523812MiAaPQMiAaPQMiAaPQBOOK9910779522303321Heart transplantation3764151UNINA