04408nam 2200601Ia 450 991077950520332120200520144314.01-61942-443-6(CKB)2550000001040685(EBL)3017867(SSID)ssj0000938788(PQKBManifestationID)11517102(PQKBTitleCode)TC0000938788(PQKBWorkID)10921989(PQKB)10094067(MiAaPQ)EBC3017867(Au-PeEL)EBL3017867(CaPaEBR)ebr10654838(OCoLC)847714924(EXLCZ)99255000000104068520120723d2012 uy 0engur|n|---|||||txtccrGhrelin[electronic resource] production, action mechanisms & physiological effects /Hiromasa Yamada and Kintaro Takahashi, editorsNew York Nova Sciencec20121 online resource (167 p.)Physiology - laboratory and clinical researchDescription based upon print version of record.1-61942-400-2 Includes bibliographical references and index.""GHRELIN: PRODUCTION, ACTION MECHANISMS AND PHYSIOLOGICAL EFFECTS""; ""GHRELIN: PRODUCTION, ACTION MECHANISMS AND PHYSIOLOGICAL EFFECTS""; ""Library of Congress Cataloging-in-Publication Data""; ""Contents""; ""Preface""; ""Chapter I: Nucleotide Polymorphisms, Transcriptional Analysis, Gene Expression of the Bovine Growth Hormone Secretagogue Receptor 1A (GHS-R1A) Gene and Its Genetic Association with Growth and Carcass Traits in Cattle""; ""Abstract""; ""Introduction""""1. Nucleotide Polymorphisms from the 5�-Flanking Region to the 3�-UTR of the GHS-R1A Gene and its Molecular Evolution""""Microsatellite ((TG)n) Polymorphism and Molecular Evolution""; ""Nucleotide Polymorphism""; ""Allele Frequency of nt-7(C>A), L24V, DelR242 and the Microsatellite ((GTTT)n)""; ""Haplotype frequency of the [microsatellite ((TG)n] � [nt-7(C>A) ] � [L24V] - [DelR242] � [microsatellite ((GTTT)n)]""; ""2. 5� -UTR Transcriptional Analysis of the Bovine GHS-R1a Gene""""3. Age-Related Changes in the GHS-R1 and GHS-R1b mRNA Expressions in Several Tissues Including the Arcuate Nucleusand Pituitary Gland""""4. Genetic Association between the 5�UTR Microsatellite ((TG)n) of the GHS-R1a Geneand Growth and Carcass Traits in Japanese Black Cattle""; ""5. The Translational Hypothesis That Any Significant Genetic Association with Growth and Carcass Traits Is Attributable to Differences in the Secondary Structure of GHS-R1b mRNA""""6. Prediction of the Potential Increase in Profitability Due to Increased Carcass Weight through Planned Matings Based on DNA testing of the 5�UTR Microsatellite ((TG)n)of the GHS-R1a gene""""Conclusion""; ""References""; ""Chapter II: The Role of the Pro-Ghrelin Derived Peptides in the Iris Muscle Regulation: Implications in Glaucoma Pathophysiology""; ""Abstract""; ""Introduction""; ""Iris Sphincter Muscle""; ""The Iris Dilator Muscle""; ""Anterior Segment""; ""Posterior Segment""; ""Other Effects in the Eye""; ""Acknowledgments""; ""References""""Chapter III: Ghrelin: Expression and Functions in the Central Nervous System""""Abstract""; ""Introduction""; ""1. Ghrelin in the Brain In Situ""; ""2. Biological Effects of Ghrelin on the Brainand the Pituitary Gland, and Mechanismof Ghrelin Activity""; ""3. Expression and Effects of Ghrelinduring Development""; ""4. Ghrelin and Memory Formation under Normal and Pathological Conditions""; ""Conclusion""; ""Acknowledgments""; ""References""; ""Chapter IV: Role of Central Ghrelin in the Gastric Accommodation and Reflex Swallowing""; ""Abstract""; ""1. Introduction""""2. Significance of the Caudal Brainstem as a Target of Ghrelin""Physiology : Laboratory and Clinical ResearchGhrelinGastrointestinal hormonesGhrelin.Gastrointestinal hormones.Yamada Hiromasa1481218Takahashi Kintaro1481219MiAaPQMiAaPQMiAaPQBOOK9910779505203321Ghrelin3698086UNINA