04704nam 2200637Ia 450 991077878360332120230331004943.01-280-21480-597866102148080-309-55775-50-585-14439-7(CKB)110986584750836(EBL)3377195(SSID)ssj0000215468(PQKBManifestationID)11202596(PQKBTitleCode)TC0000215468(PQKBWorkID)10194336(PQKB)10198298(MiAaPQ)EBC3377195(Au-PeEL)EBL3377195(CaPaEBR)ebr10068430(CaONFJC)MIL21480(OCoLC)940510378(EXLCZ)9911098658475083619890811d1989 uy 0engur|n|---|||||txtccrOpportunities in biology[electronic resource] /Committee on Research Opportunities in Biology, Board in Biology, Commission on Life Sciences, National Research CouncilWashington National Academy Press19891 online resource (470 p.)Includes index.0-309-07881-4 0-309-03927-4 Includes bibliographical references (p. 422-423).Opportunities in Biology; Copyright; Acknowledgments; Preface; Contents; Executive Summary; THE NEW BIOLOGY; STRUCTURAL BIOLOGY; GENES AND CELLS; DEVELOPMENT; THE NERVOUS SYSTEM AND BEHAVIOR; THE IMMUNE SYSTEM AND INFECTIOUS DISEASES; EVOLUTION, SYSTEMATICS, AND ECOLOGY; PLANT BIOLOGY AND AGRICULTURE; INFRASTRUCTURE OF BIOLOGY RESEARCH AND RECOMMENDATIONS; Training; Equipment and Facilities; Funding; Information Science and Collections; International Cooperation; 1 The New Biology; DIVISIONS BETWEEN TRADITIONAL DISCIPLINES ARE BEING REMOVED; 2 New Technologies and InstrumentationRECOMBINANT DNA TECHNIQUESRecombinant DNA Techniques Permit us to Isolate a Single Gene From the Tens of Thousands Encoded in a Complex Genome; Transformation of Higher Organisms; Biologists Can Specifically Insert a Functioning Gene Into the Genome of Complex Organisms; Making a Transgenic Animal; A Transgenic Animal is Produced Initially by a Combination of Microsurgery And Embryological Techniques; Transgenic Mice Have Been Used For a Variety of Experiments; Creating Transgenic Plants; The Creation of Transformed Plants Has Been one of The Most Exciting Developments in Modern BiologyFuture ProspectsThe Potential for Using Transgenic Organisms to Make Discoveries Over the Next 5 or 10 Years Is Vast; MONOCLONAL ANTIBODIES; Monoclonal Antibodies Can be Used as Biological Probes For Specific Molecules; MICROCHEMICAL TECHNIQUES; Microchemical Instrumentation Has Had a Powerful Impact on Modern Biology That is Just Beginning to be Felt; FLOW CYTOMETRY; Flow Cytometry is Used to Sort Cells; MICROSCOPY; A Revolution in the Application of Light Microscopy Has Occurred; Video-Enhanced Contrast MicroscopyVideo-Enhanced Contrast Microscopy Combines the Technologies of Modern Light Microscopy, Video Imaging, and Digital Image...Low-Light-Dose Microscopy; Coupling Biological Chemistry with Advanced Image Processing Has Permitted Low-Light-Dose Microscopy to Evolve as an...; Scanning Acoustic Microscope; The Scanning Acoustic Microscope Measures the Elastic Properties of the Cell; Scanning Tunneling and Atomic Force Microscope; The Scanning Tunneling Microscope Allows One to Image Surfaces with the Resolution of an Few AngstromsThe Atomic Force Microscope Holds Great Promise for Analyzing Biological SpecimensMAGNETIC RESONANCE; Magnetic Resonance Spectroscopy is Becoming an Invaluable Tool for Determining the Structures of Complex Molecules; COMPUTERS AND DATA ANALYSIS; Computers are Coming to Play an Central Role in Modern Biology; BIOLOGY AND THE FUTURE; Synergistic Interactions of the New Biology Have Shortened the Time Between Fundamental Observations and Applications; 3 Molecular Structure and Function; Biological Macromolecules are MachinesThe Main Theme of Structural Biology Is the Relation of Molecular Structure to FunctionBiologyResearchLife sciencesResearchBiologyResearch.Life sciencesResearch.574/.072National Research Council (U.S.).Committee on Research Opportunities in Biology.MiAaPQMiAaPQMiAaPQBOOK9910778783603321Opportunities in biology3859215UNINA