02996nam 2200577Ia 450 991077871190332120231009231128.01-280-22163-197866102216390-309-55513-20-585-14460-5(CKB)111004366657404(OCoLC)427404809(CaPaEBR)ebrary10062946(SSID)ssj0000127240(PQKBManifestationID)11139730(PQKBTitleCode)TC0000127240(PQKBWorkID)10051710(PQKB)10480426(MiAaPQ)EBC3377011(Au-PeEL)EBL3377011(CaPaEBR)ebr10062946(OCoLC)923267638(EXLCZ)9911100436665740419870928d1988 uy 0engurcn|||||||||txtrdacontentcrdamediacrrdacarrierComplex mixtures methods for in vivo toxicity testing /Committee on Methods for the In Vivo Toxicity Testing of Complex Mixtures, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research CouncilWashington, D.C. :National Academy Press,1988.1 online resource (xi, 227 pages) illustrationsBibliographic Level Mode of Issuance: Monograph0-309-03778-6 Includes bibliographies and index.1 Front Matter; 2 Executive Summary; 3 1. Introduction; 4 2. Concepts for Analyzing Human Exposure to Complex Chemical Mixtures; 5 3. Testing Strategies and Methods; 6 4. Sampling and Chemical Characterization; 7 5. Interpretation and Modeling of Toxicity-Test Results; 8 Appendix A: Origins of Complex Mixtures; 9 Appendix B: Case Studies Establishing Active Agents and/or Interactions in Complex Mixtures; 10 Appendix C: Case Studies on Strategies for Testing the Toxicity of Complex Mixtures; 11 Appendix D: Predicting the Joint Risk of a Misture in Terms of the Component Risks; 12 Appendix E: Cancer Models; 13 Appendix F: Developmental Toxicology; 14 Appendix G: Empirical Modeling of the Toxicity of Mixtures; 15 IndexAddresses the problem of identifying and classifying complex mixtures, investigating the effect of exposure, and the research problems inherent in testing their toxicity to human beings. A series of case studies is presented, including one that examines the cofactors of alcohol consumption and cigarette smoke.Toxicity testingEvaluationToxicology, ExperimentalToxicity testingEvaluation.Toxicology, Experimental.615.9/07National Research Council (U.S.).Committee on Methods for the In Vivo Toxicity Testing of Complex Mixtures.MiAaPQMiAaPQMiAaPQBOOK9910778711903321Complex mixtures3731914UNINA