05434nam 2200685Ia 450 991077864150332120230422031318.01-280-18559-797866101855970-309-57146-40-585-21934-6(CKB)110986584752954(EBL)3376737(SSID)ssj0000237581(PQKBManifestationID)12085245(PQKBTitleCode)TC0000237581(PQKBWorkID)10191596(PQKB)11444544(MiAaPQ)EBC3376737(Au-PeEL)EBL3376737(CaPaEBR)ebr10057014(CaONFJC)MIL18559(OCoLC)817960589(EXLCZ)9911098658475295420040924d2000 my 0engurcn|||||||||txtccrReview of the Hanford thyroid disease study draft final report[electronic resource] /Committee on an Assessment of Centers for Disease Control and Prevention Radiation Studies from DOE Contractor Sites ; Subcommittee to Review the Hanford Thyroid Disease Study Final Results and Report, Board on Radiation Effects Research, Commission on Life Sciences, National Academy of SciencesWashington, D.C. National Academy Press20001 online resource (228 p.)Description based upon print version of record.0-309-06883-5 Includes bibliographical references.""Review of the Hanford Thyroid Disease Study Draft Final Report""; ""Copyright""; ""ACKNOWLEDGEMENTS""; ""Contents""; ""Public Summary""; ""BACKGROUND""; ""DESIGN OF THE HTDS""; ""Estimated Radiation Exposures""; ""Analysis of HTDS Data""; ""Statistical Power and the HTDS Interpretation""; ""Communication of HTDS Results to the Public""; ""Concluding Remarks""; ""Executive Summary""; ""BACKGROUND""; ""EPIDEMIOLOGIC AND CLINICAL METHODS AND DATA COLLECTION""; ""Conclusions:""; ""Recommendations:""; ""DOSIMETRY""; ""Conclusions:""; ""Recommendations:""; ""STATISTICAL ANALYSES""""Conclusions:""""Recommendations:""; ""STATISTICAL POWER AND INTERPRETATION OF THE STUDY""; ""Conclusions:""; ""Recommendations:""; ""COMMUNICATION OF THE STUDY RESULTS TO THE PUBLIC""; ""Conclusions:""; ""Recommendations:""; ""SUMMARY OF RESPONSES TO THE CDC'S QUESTIONS""; ""1 Introduction ""; ""2 Overview of the HTDS Draft Final Report and Organization of the Committee's Report ""; ""3 Evaluation of Epidemiologic and Clinical Methods ""; ""EVALUATION OF EPIDEMIOLOGIC METHODS""; ""MILK-CONSUMPTION ESTIMATION""; ""EVALUATION OF CLINICAL-DATA COLLECTION""""COMPLETENESS OF ASCERTAINMENT OF THYROID DISEASE""""SUSCEPTIBILITY FACTORS FOR THYROID DISEASE""; ""EVALUATION OF MORTALITY DATA""; ""AMERICAN INDIAN TRIBAL ISSUES""; ""4 Evaluation of Dosimetric Methods and Results ""; ""BACKGROUND""; ""HEDR CALCULATIONS OF ENVIRONMENTAL CONCENTRATIONS OF 131 I FROM HANFORD AND RESULTING DOSES: ASSESS ME...""; ""Source Term:""; ""Concentration of 131 I in Pasture Grass at Time of Fallout:""; ""Mean Time of Residence of 131I on Pasture Grass:""; ""Pasture Intake by Cows:""; ""Transfer Coefficient of 131I from Cow's Intake to Milk:""""Milk-Distribution Factor:""""Milk-Consumption Rate:""; ""Thyroid Dose Coefficient:""; ""HEDR DOSIMETRY-MODEL VALIDATION""; ""Thyroid Burdens""; ""Milk Concentrations""; ""Concentrations in Vegetation""; ""Concentrations in Air""; ""Conclusions""; ""Possible Underestimation or Overestimation of Doses""; ""DOSE UNCERTAINTIES""; ""131 I FROM THE NEVADA TEST SITE AND GLOBAL FALLOUT""; ""OTHER SOURCES OF RADIATION EXPOSURE""; ""5 Evaluation of Statistical Data Analysis ""; ""MODE OF PRESENTATION OF RESULTS""; ""TYPES OF ANALYSES AND RELATED DOSIMETRY-ERROR ISSUES""""ANALYSIS OF POTENTIAL CONFOUNDING OR EFFECT-MODIFYING VARIABLES""""ASSUMPTION OF EQUIVALENT RADIATION EFFECT FOR MALES AND FEMALES""; ""ANALYSES BY AGE AT EXPOSURE""; ""OUT-OF-AREA ANALYSES""; ""GEOSTRATUM VERSUS DISEASE""; ""GENERAL-POPULATION COMPARISON AND SCREENING ISSUES""; ""ANALYSES OF SOURCE OF PERSONAL-EXPOSURE INFORMATION""; ""6 Statistical Power and Interpretation of the Study ""; ""FACTORS IN STATISTICAL POWER""; ""SAMPLE SIZE AND ASSUMED BACKGROUND PREVALENCE OF DISEASE""; ""EFFECT OF DOSIMETRY ERROR ON STATISTICAL POWER""; ""VIOLATION OF THE BERKSON ERROR ASSUMPTION""""DOSE ERROR DUE TO UNCERTAINTIES IN INPUT DATA""Thyroid glandDiseasesEpidemiologyResearchWashington (State)MethodologyThyroid glandDiseasesEpidemiologyResearchOregonMethodologyIonizing radiationToxicologyWashington (State)Ionizing radiationToxicologyOregonHanford Site (Wash.)Thyroid glandDiseasesEpidemiologyResearchMethodology.Thyroid glandDiseasesEpidemiologyResearchMethodology.Ionizing radiationToxicologyIonizing radiationToxicology614.5/944/00979751National Academy of Sciences (U.S.)MiAaPQMiAaPQMiAaPQBOOK9910778641503321Review of the Hanford thyroid disease study draft final report3753029UNINA