05360nam 22007094a 450 991077861030332120230422035845.00-309-18354-51-280-18513-997866101851390-309-56508-1(CKB)110986584753258(EBL)3377264(SSID)ssj0000097020(PQKBManifestationID)11128052(PQKBTitleCode)TC0000097020(PQKBWorkID)10103929(PQKB)10240149(MiAaPQ)EBC3377264(Au-PeEL)EBL3377264(CaPaEBR)ebr10068511(OCoLC)923269359(EXLCZ)9911098658475325820070309d2000 uy 0engur|n|---|||||txtccrAcute exposure guideline levels for selected airborne chemicals[electronic resource] /Subcommittee on Acute Exposure Guideline Levels, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission of Life Sciences, National Research CouncilWashington, D.C. National Academy Pressc20001 online resource (219 p.)The compass seriesDescription based upon print version of record.0-309-07294-8 Includes bibliographical references.""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Copyright""; ""Preface""; ""Contents""; ""Acute Exposure Guideline Levels for Selected Airborne Chemicals""; ""Introduction""; ""SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING AEGLS""; ""REVIEW OF AEGL REPORTS""; ""REFERENCES""; ""Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances""; ""COMMITTEE MEMBERS""; ""OAK RIDGE NATIONAL LABORATORY STAFF""; ""NATIONAL ADVISORY COMMITTEE STAFF""; ""Appendix""; ""1 Aniline1 Acute Exposure Guideline Levels""; ""SUMMARY""""1. INTRODUCTION""""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Experimental Studies""; ""2.2.2. Epidemiology Studies""; ""2.2.3. Accidents""; ""2.3. Developmental and Reproductive Effects""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Rats""; ""3.1.2. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Dogs""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4 Guinea pigs""; ""3.3. Developmental and Reproductive Effects""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity""""3.6. Summary""""4. SPECIAL CONSIDERATIONS""; ""4.1. Metabolism and Disposition""; ""4.2. Mechanism of Toxicity""; ""4.3. Structure-Activity Relationships""; ""4.4. Other Relevant Information""; ""4.4.1. Susceptible Subpopulations""; ""4.4.2. Species Differences""; ""4.4.3. Concentration-Exposure Duration Relationship""; ""5. DATA ANALYSIS FOR AEGL-1""; ""5.1. Human Data Relevant to AEGL-1""; ""5.2. Animal Data Relevant to AEGL-1""; ""5.3. Derivation of AEGL-1""; ""6. DATA ANALYSIS FOR AEGL-2""; ""6.1. Human Data Relevant to AEGL-2""; ""6.2. Animal Data Relevant to AEGL-2""""6.3. Derivation of AEGL-2""""7. DATA ANALYSIS FOR AEGL-3""; ""7.1. Human Data Relevant to AEGL-3""; ""7.2. Animal Data Relevant to AEGL-3""; ""7.3. Derivation of AEGL-3""; ""8. SUMMARY OF AEGLS""; ""8.1. AEGL Values and Toxicity Endpoints""; ""8.2. Comparisons with Other Standards and Guidelines""; ""8.3. Data Adequacy and Research Needs""; ""9. REFERENCES""; ""2 Arsine1 Acute Exposure Guideline Levels""; ""SUMMARY""; ""1. INTRODUCTION""; ""2. HUMAN TOXICITY DATA""; ""2.1. Acute Lethality""; ""2.1.1. Case Reports""; ""2.2. Nonlethal Toxicity""; ""2.2.1. Case Reports""""2.2.2. Epidemiologic Studies""""2.3. Developmental and Reproductive Toxicity""; ""2.4. Genotoxicity""; ""2.5. Carcinogenicity""; ""2.6. Summary""; ""3. ANIMAL TOXICITY DATA""; ""3.1. Acute Lethality""; ""3.1.1. Nonhuman Primates""; ""3.1.2. Dogs""; ""3.1.3. Cats""; ""3.1.4 Rats""; ""3.1.5. Mice""; ""3.2. Nonlethal Toxicity""; ""3.2.1. Nonhuman Primates""; ""3.2.2. Rats""; ""3.2.3. Mice""; ""3.2.4. Hamsters""; ""3.3. Developmental/Reproductive Toxicity""; ""3.3.1. Rats""; ""3.3.2. Mice""; ""3.4. Genotoxicity""; ""3.5. Carcinogenicity""; ""3.6. Summary""; ""4. SPECIAL CONSIDERATIONS""""4.1. Metabolism and Disposition""Compass series (Washington, D.C.)Gases, Asphyxiating and poisonousHazardous substancesEnvironmental aspectsHazardous substancesHealth aspectsChemicalsPhysiological effectChemicalsHealth aspectsGases, Asphyxiating and poisonous.Hazardous substancesEnvironmental aspects.Hazardous substancesHealth aspects.ChemicalsPhysiological effect.ChemicalsHealth aspects.615.9/1National Research Council (U.S.).Subcommittee on Acute Exposure Guideline Levels.MiAaPQMiAaPQMiAaPQBOOK9910778610303321Acute exposure guideline levels for selected airborne chemicals2610632UNINA