03211nam 2200733Ia 450 991077845360332120230721022955.00-674-04212-310.4159/9780674042124(CKB)1000000000805582(OCoLC)456276613(CaPaEBR)ebrary10318531(SSID)ssj0000161314(PQKBManifestationID)11163088(PQKBTitleCode)TC0000161314(PQKBWorkID)10191030(PQKB)10257655(MiAaPQ)EBC3300534(DE-B1597)457734(OCoLC)1013954096(OCoLC)1029819685(OCoLC)1032690457(OCoLC)1037981461(OCoLC)1042034731(OCoLC)1046605271(OCoLC)1047007519(OCoLC)979683503(DE-B1597)9780674042124(Au-PeEL)EBL3300534(CaPaEBR)ebr10318531(OCoLC)923111690(EXLCZ)99100000000080558220060516d2007 uy 0engurcn|||||||||txtccrGene sharing and evolution[electronic resource] the diversity of protein functions /Joram PiatigorskyCambridge, Mass. Harvard University Press20071 online resource (337 p.) Bibliographic Level Mode of Issuance: Monograph0-674-02341-2 Includes bibliographical references (p. 241-305) and index.Frontmatter -- Contents -- Illustrations -- Preface -- 1. What Is "Gene Sharing"? -- 2. Multifunctions and Functional Shifts: Echos from the Past -- 3. The Elusive Concept of a "Gene" -- 4. Eyes and Lenses: Gene Sharing by Crystallins -- 5. The Enigmatic "Corneal Crystallins": Putative Cases of Gene Sharing -- 6. Gene Sharing as a Common Event: Many Multifunctional Proteins -- 7. Gene Sharing during Gene Expression -- 8. Gene Sharing As a Dynamic Evolutionary Process: Antifreeze Proteins and Hemoglobins -- 9. Gene Duplication and the Evolution of New Functions -- 10. Gene Sharing and Systems Biology: Implications and Speculations -- 11. Recapitulations: Ambiguities and Possibilities -- Glossary -- References -- IndexIn Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution.Genetic regulationProteinsEvolutionEyeMolecular aspectsCrystalline lensGenetic regulation.ProteinsEvolution.EyeMolecular aspects.Crystalline lens.572/.6WG 1940rvkPiatigorsky Joram1512542MiAaPQMiAaPQMiAaPQBOOK9910778453603321Gene sharing and evolution3746489UNINA