03664nam 2200601Ia 450 991077819310332120231011233741.00-674-03943-210.4159/9780674039438(CKB)1000000000786753(EBL)3300495(SSID)ssj0000119393(PQKBManifestationID)11131970(PQKBTitleCode)TC0000119393(PQKBWorkID)10056530(PQKB)10903666(Au-PeEL)EBL3300495(CaPaEBR)ebr10318489(OCoLC)923112038(DE-B1597)571827(DE-B1597)9780674039438(MiAaPQ)EBC3300495(OCoLC)1294424518(EXLCZ)99100000000078675320040316h20022000 uy 0engur|n|---|||||txtccrThe century of the gene[electronic resource] /Evelyn Fox KellerCambridge, Mass. Harvard University Press2002, c20001 online resource (192 p.)Description based upon print version of record.0-674-00372-1 0-674-00825-1 Includes bibliographical references (p. [169]-182) and index.Frontmatter --CONTENTS --Introduction: The Life of a Powerful Word --1. Motors of Stasis and Change: The Regulation of Genetic Stability --2. The Meaning of Gene Function: What Does a Gene Do? --3. The Concept of a Genetic Program: How to Make an Organism --4. Limits of Genetic Analysis: What Keeps Development on Track? --Conclusion: What Are Genes For? --Notes --References --Acknowledgments --IndexIn a book that promises to change the way we think and talk about genes and genetic determinism, Evelyn Fox Keller, one of our most gifted historians and philosophers of science, provides a powerful, profound analysis of the achievements of genetics and molecular biology in the twentieth century, the century of the gene. Not just a chronicle of biology’s progress from gene to genome in one hundred years, The Century of the Gene also calls our attention to the surprising ways these advances challenge the familiar picture of the gene most of us still entertain. Keller shows us that the very successes that have stirred our imagination have also radically undermined the primacy of the gene—word and object—as the core explanatory concept of heredity and development. She argues that we need a new vocabulary that includes concepts such as robustness, fidelity, and evolvability. But more than a new vocabulary, a new awareness is absolutely crucial: that understanding the components of a system (be they individual genes, proteins, or even molecules) may tell us little about the interactions among these components. With the Human Genome Project nearing its first and most publicized goal, biologists are coming to realize that they have reached not the end of biology but the beginning of a new era. Indeed, Keller predicts that in the new century we will witness another Cambrian era, this time in new forms of biological thought rather than in new forms of biological life.GeneticsHistory20th centuryBiologyHistoryGeneticsHistoryBiologyHistory.576.5WB 2415rvkKeller Evelyn Fox1936-2023.1462633MiAaPQMiAaPQMiAaPQBOOK9910778193103321The century of the gene3687806UNINA