03117nam 22006494a 450 991077778060332120230828235043.01-281-73047-597866117304750-300-12970-X10.12987/9780300129700(CKB)1000000000472014(StDuBDS)AH23049610(SSID)ssj0000233951(PQKBManifestationID)11202524(PQKBTitleCode)TC0000233951(PQKBWorkID)10235606(PQKB)10705938(MiAaPQ)EBC3419998(DE-B1597)484980(OCoLC)952732441(DE-B1597)9780300129700(Au-PeEL)EBL3419998(CaPaEBR)ebr10170024(OCoLC)923589448(EXLCZ)99100000000047201420051114d2006 uy 0engur|||||||||||txtccrReconceiving the gene[electronic resource] Seymour Benzer's adventures in phage genetics /Frederic Lawrence Holmes ; edited by William C. SummersNew Haven Yale University Pressc20061 online resource (352 p.) Bibliographic Level Mode of Issuance: Monograph0-300-11078-2 Includes bibliographical references (p. [303]-329) and index.Classical mendelian genetics -- Genetics and the phage biologists -- The physicist becomes a phage biologist -- To Paris and back -- Teaching and research at Purdue -- Entering the rII region -- Crossing into the fine structure -- Is gene a dirty word? -- The survival of the "gene".This book relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial virus known as phage T4. Benzer's accomplishments are widely recognized as a tipping point in mid-twentieth-century molecular biology when the nature of the gene was recast in molecular terms. More often than any other individual, he is considered to have led geneticists from the classical gene into the molecular age. Drawing on Benzer's remarkably complete record of his experiments, his correspondence, and published sources, this book reconstructs how the former physicist initiated his work in phage biology and achieved his landmark investigation. The account of Benzer's creativity as a researcher is a fascinating story that also reveals intriguing aspects common to the scientific enterprise.GeneticistsUnited StatesBiographyBacteriophagesGeneticsViral geneticsHistoryGeneticistsBacteriophagesGenetics.Viral geneticsHistory.576.5092BHolmes Frederic Lawrence726772Summers William C1536798MiAaPQMiAaPQMiAaPQBOOK9910777780603321Reconceiving the gene3785726UNINA