04018oam 22007814a 450 991077751670332120190503073334.00-262-25706-81-282-09679-697866120967921-4237-7254-7(CKB)1000000000461545(EBL)3338535(SSID)ssj0000254896(PQKBManifestationID)11191653(PQKBTitleCode)TC0000254896(PQKBWorkID)10209040(PQKB)10290000(StDuBDS)EDZ0000130826(CaBNVSL)mat06267344(IDAMS)0b000064818b4332(IEEE)6267344(OCoLC)68816342(OCoLC)182530572(OCoLC)473746717(OCoLC)648224453(OCoLC)655188713(OCoLC)704103076(OCoLC)888573911(OCoLC)961526465(OCoLC)962598445(OCoLC)988420642(OCoLC)992036296(OCoLC)1037506181(OCoLC)1037911808(OCoLC)1038673673(OCoLC)1083558586(OCoLC-P)68816342(MaCbMITP)6604(Au-PeEL)EBL3338535(CaPaEBR)ebr10173591(CaONFJC)MIL209679(OCoLC)815776335(MiAaPQ)EBC3338535(PPN)261608673(EXLCZ)99100000000046154520060515d2006 uy 0engur|n|---|||||txtccrSystem modeling in cell biology from concepts to nuts and bolts /edited by Zoltan Szallasi, Jörg Stelling, Vipul PeriwalCambridge, Mass. MIT Press©20061 online resource (465 p.)"A Bradford book."0-262-19548-8 Includes bibliographical references (p. [385]-433) and index.Contents; Preface; I GENERAL CONCEPTS; 1 The Role of Modeling in Systems Biology; 2 Complexity and Robustness of Cellular Systems; 3 On Modules and Modularity; II MODELING APPROACHES; 4 Bayesian Inference of Biological Systems: The Logic of Biology; 5 Stoichiometric and Constraint-based Modeling; 6 Modeling Molecular Interaction Networks with Nonlinear Ordinary Differential Equations; 7 Qualitative Approaches to the Analysis of Genetic Regulatory Networks; 8 Stochastic Modeling of Intracellular Kinetics; 9 Kinetics in Spatially Extended Systems; III MODELS AND REALITY10 Biological Data Acquisition for System Level Modeling-An Exercise in the Art of Compromise11 Methods to Identify Cellular Architecture and Dynamics from Experimental Data; 12 Using Control Theory to Study Biology*; 13 Synthetic Gene Regulatory Systems; 14 Multilevel Modeling in Systems Biology: From Cells to Whole Organs; IV COMPUTATIONAL MODELING; 15 Computational Constraints on Modeling in Systems Biology; 16 Numerical Simulation for Biochemical Kinetics; 17 Software Infrastructure for Effective Communication and Reuse of Computational Models; A Software Tools for Biological ModelingReferencesContributors; IndexThis is an introduction and overview of system modelling in biology that is accessible to researchers from different fields including biology, computer science, mathematics, statistics physics, and biochemistry.System modeling in cellular biologyCytologyData processingCytologyMathematical modelsCytologyComputer simulationBiological systemsBIOMEDICAL SCIENCES/Quantitative BiologyCytologyData processing.CytologyMathematical models.CytologyComputer simulation.Biological systems.571.601/1Szallasi Zoltan1467526Stelling Jörg1467527Periwal Vipul1467528OCoLC-POCoLC-PBOOK9910777516703321System modeling in cell biology3678204UNINA