05059nam 22006255 450 991076756480332120231124005145.03-031-37936-510.1007/978-3-031-37936-9(MiAaPQ)EBC30967773(Au-PeEL)EBL30967773(DE-He213)978-3-031-37936-9(CKB)29030218800041(EXLCZ)992903021880004120231123d2024 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierSyncytia: Origin, Structure, and Functions /edited by Malgorzata Kloc, Ahmed Uosef1st ed. 2024.Cham :Springer International Publishing :Imprint: Springer,2024.1 online resource (480 pages)Results and Problems in Cell Differentiation,1861-0412 ;71Print version: Kloc, Malgorzata Syncytia: Origin, Structure, and Functions Cham : Springer International Publishing AG,c2023 Part I. Germline Syncytia, Evolution, Function, and Structure -- Chapter 1. The Ancient Origin and Function of Germline Cysts -- Chapter 2. Female Germline Cysts in Animals: Evolution and Function -- Chapter 3. Germline and Somatic Cell Syncytia in Insects -- Part II. Syncytia in Embryogenesis and Development -- Chapter 4. Reshaping the Syncytial Drosophila Embryo with Cortical Actin Networks: Four Main Steps of Early Development -- Chapter 5. Cell-Mediated Branch Fusion in the Drosophila Trachea -- Chapter 6. Trophoblast Syncytialization: A Metabolic Crossroads -- Chapter 7. Early Syncytialization of the Ovine Placenta Revisited -- Chapter 8. Syncytia in Utricularia: Origin and Structure -- Part III. Fungal and Somatic Cell Syncytia and Genomic View of Extremophiles as the Ancestral Precursors of Eukaryotic Syncytia -- Chapter 9. Syncytial Assembly Lines: Consequences of Multinucleate Cellular Compartments for Fungal Protein Synthesis -- Chapter 10. Ancestors in The Extreme: A Genomics View of Microbial Diversity in Hypersaline Aquatic Environments -- Chapter 11. Somatic Cell Fusion in Host Defense and Adaptation -- Chapter 12. Osteoclasts at Bone Remodeling: Order from Order -- Chapter 13. Muscle Progenitor Cell Fusion in the Maintenance of Skeletal Muscle -- Part IV. Virus- and Parasite- Induced Syncytia -- Chapter 14. Virus-Induced Cell Fusion and Syncytia Formation -- Chapter 15. HIV-1 Induced Cell-to-Cell Fusion or Syncytium Formation -- Chapter 16. Relevance of the Entry by Fusion at the Cytoplasmic Membrane vs. Fusion After Endocytosis in the HIV and SARS-Cov-2 Infections -- Chapter 17. Mathematical Modeling of Virus-Mediated Syncytia Formation: Past Successes and Future Directions -- Chapter 18. Syncytium Induced by Plant-Parasitic Nematodes -- Part V. Cell Fusion and Syncytia in Cancer -- Chapter 19. Mechanisms of Cell Fusion in Cancer -- Chapter 20. Cell Fusion and Syncytia Formation in Cancer -- Chapter 21. The Hallmarks of Circulating Hybrid Cells.This book gives a current overview on the development, origin, structure, and functions of germline and somatic cell syncytia during embryogenesis and organogenesis. It also reviews pathogen-induced syncytia and the role of syncytial cells in cancer development. The book covers the following topics: germline syncytia, evolution, function and structure; syncytia in embryogenesis and development; the role of somatic cell fusion in fungi, specialized somatic tissues, host defense and adaptation; syncytia induced by viruses and parasites; syncytia and circulating hybrid cells in cancer and other pathological conditions; It also discusses how the genomic adaptations of microorganisms to extreme habitats can prompt the evolution of mononuclear and multinucleate/syncytial cells. The book offers a fresh outlook on syncytia's role in various processes: embryogenesis, organogenesis, adaptation, host defense, and development of specialized tissues. It highlights the importance of syncytia under physiological and pathological conditions.Results and Problems in Cell Differentiation,1861-0412 ;71Cell differentiationDevelopmental biologyStem cellsCytologyCell DifferentiationDevelopmental Biology and Stem CellsStem Cell BiologyCell BiologyCell differentiation.Developmental biology.Stem cells.Cytology.Cell Differentiation.Developmental Biology and Stem Cells.Stem Cell Biology.Cell Biology.571.845Kloc Malgorzata1453555Uosef Ahmed1453556MiAaPQMiAaPQMiAaPQBOOK9910767564803321Syncytia: Origin, Structure, and Functions3656201UNINA