02383nam 2200385 450 991076553820332120240215175051.01-83768-400-6(CKB)5580000000706380(NjHacI)995580000000706380(EXLCZ)99558000000070638020240215d2023 uy 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierThalassemia Syndromes - New Insights and Transfusion Modalities /Marwa Zakaria (and three others)London :IntechOpen,2023.1 online resource (242 pages)1-83768-399-9 1. Overview of Beta-Thalassemia -- 2. Effects of Beta-Thalassemia on COVID-19 Outcomes -- 3. Newborn Screening and Thalassaemia Syndrome -- 4. The Key Genetic Determinants Behind the Phenotypic Heterogeneity of HbE/β-thalassemia Patients and the Probable Management Strategy -- 5. Interaction of Thalassemia and Hb Variants in Southeast Asia: Genotype-Phenotype Relationship -- 6. The Thalassemia Syndromes: New Insights -- 7. Optimizing Blood Transfusion Service Delivery across the West African Sub-Region -- 8. Clinical Effects and Possible Mechanisms of Transfusion-Related Immunomodulation -- 9. Personnel for Blood Transfusion Services in Nigeria: A Multicenter Cooperative Study.The thalassemia syndromes are a diverse group of hereditary anemias caused by decreased or absent production of one type of globin chain. Genetic counseling, prenatal diagnosis, and newborn screening are all issues of importance in these inherited disorders. This book provides a comprehensive overview of thalassemia, including information on its mechanisms and treatment modalities. Chapters elucidate the mechanism of disordered synthesis of hemoglobin in thalassemia and present recent studies of the genetic mechanisms that underlie this abnormal biosynthetic process.ThalassemiaLaw and legislationThalassemiaThalassemiaLaw and legislation.Thalassemia.616.152Marwa ZakariaNjHacINjHaclBOOK9910765538203321Thalassemia Syndromes - New Insights and Transfusion Modalities3654092UNINA