04593nam 22007335 450 991074609820332120251128155604.03-031-26098-810.1007/978-3-031-26098-8(MiAaPQ)EBC30739079(Au-PeEL)EBL30739079(DE-He213)978-3-031-26098-8(OCoLC) 1397569558(PPN)27273909X(CKB)28204510400041(EXLCZ)992820451040004120230911d2023 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierClinical Neuroembryology Development and Developmental Disorders of the Human Central Nervous System /by Hans J. ten Donkelaar, Martin Lammens, Akira Hori3rd ed. 2023.Cham :Springer International Publishing :Imprint: Springer,2023.1 online resource (926 pages)Print version: ten Donkelaar, Hans J. Clinical Neuroembryology Cham : Springer International Publishing AG,c2023 9783031260971 Includes bibliographical references and index.Overview of the Development of the Human Brain and Spinal Cord -- Mechanisms of Development -- Causes of Congenital Malformations -- Neurulation and Neurulation Defects -- The Neural Crest and Craniofacial Malformations -- Development and Developmental Disorders of the Spinal Cord -- Development and Developmental Disorders of the Brain Stem -- Development and Developmental Disorders of the Human Cerebellum -- Development and Developmental Disorders of the Forebrain -- Development and Developmental Disorders of the Cerebral Cortex.This book provides a comprehensive overview of the development of the human central nervous system (CNS) in the context of its many developmental disorders due to genetic, environmental and hypoxic/ischaemic causes. The book contains three general, introductory chapters in which an overview of the development of the human brain and spinal cord, a summary of mechanisms of development as obtained in experimental studies in various invertebrates and vertebrates, and an overview of the causes of congenital malformations are presented. The developmental disorders of the human brain and spinal cord are presented in a regional, more or less segmental way, starting with neurulation and neural tube defects, and ending with developmental disorders of the cerebral cortex. These chapters are abundantly illustrated in colour with carefully chosen clinical case studies with imaging data, and when available, postmortem verification of the developmental disorders involved. In the third edition, more emphasis has been given to the developmental ontology based on the prosomeric approach, and fetal development. Prenatal diagnosis by ultrasound, MRI and DTI, and classifications of developmental disorders have been updated. A number of new Clinical Cases have been included. Several new co-authors participate in various chapters. The book is intended for advanced medical students, and all those clinicians working with children and adults with developmental disorders of the CNS. Unique to the book is the integration of data from human embryology, experimental and molecular findings in mice in particular, imaging and developmental neuropathology.Developmental neurobiologyNeuroanatomyNervous systemDiseasesNeurosciencesNeurologyDevelopment of the Nervous SystemNeuroanatomyNeurological DisordersNeuroscienceNeurologyNeurobiologia del desenvolupamentthubMalalties del sistema nerviós centralthubLlibres electrònicsthubDevelopmental neurobiology.Neuroanatomy.Nervous systemDiseases.Neurosciences.Neurology.Development of the Nervous System.Neuroanatomy.Neurological Disorders.Neuroscience.Neurology.Neurobiologia del desenvolupamentMalalties del sistema nerviós central612.8ten Donkelaar Hans J.897748MiAaPQMiAaPQMiAaPQBOOK9910746098203321Clinical Neuroembryology2519595UNINA