03090nam 22005895 450 991074369590332120230901134524.03-031-40047-X10.1007/978-3-031-40047-6(MiAaPQ)EBC30727056(Au-PeEL)EBL30727056(DE-He213)978-3-031-40047-6(PPN)272735256(CKB)28141334100041(EXLCZ)992814133410004120230901d2023 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierPrecision Medicine /edited by Ingolf Cascorbi, Matthias Schwab1st ed. 2023.Cham :Springer International Publishing :Imprint: Springer,2023.1 online resource (285 pages)Handbook of Experimental Pharmacology,1865-0325 ;280Print version: Cascorbi, Ingolf Precision Medicine Cham : Springer International Publishing AG,c2023 9783031400469 Part 1. Pharmacogenomics -- Building evidence in RCTs Implementation of pharmacogenomics in healthcare in the UK -- Part 2. Precision medicine in clinical entities -- Precision medicine in therapy of non-solid cancer -- Molecular Mechanisms of Tyrosine Kinase Inhibitor Resistance in Chronic Myeloid Leukemia -- Precision medicine in Asthma -- Precision medicine in Diabetes -- Precision Medicine in Antidepressants Treatment -- Precision Medicine in Neuropathic Pain -- Part 3. Techniques in Precision Medicine -- Imaging techniques in pharmacological precision medicine -- Challenges to use NGS data to optimize drug therapy -- Part 4. Economics -- Pharmacoeconomics in precision medicine. .The rapidly increased understanding of the molecular background of complex diseases facilitated the development of highly advanced therapeutic concepts. Such concepts aiming to consider individual signatures of genomic and proteomic biomarkers including pharmacogenomics as well as advanced diagnostic tools have been successfully implemented in clinical practice in various fields leading to significant improvement of treatment successes. This volume gives an up-to-date overview on applications of precision medicine in various clinical entities, on advanced techniques as well as on economic considerations.Handbook of Experimental Pharmacology,1865-0325 ;280PharmacologyInternal medicineCancerPharmacologyInternal MedicineCancer BiologyPharmacology.Internal medicine.Cancer.Pharmacology.Internal Medicine.Cancer Biology.615Cascorbi Ingolf1426803Schwab Matthias1426804MiAaPQMiAaPQMiAaPQBOOK9910743695903321Precision Medicine3559174UNINA