03690nam 2200901z- 450 991074327600332120230911(CKB)5690000000228548(oapen)doab113987(EXLCZ)99569000000022854820230920c2023uuuu -u- -engurmn|---annantxtrdacontentcrdamediacrrdacarrierConverging Nanochemistry: From Disease Prevention to Diagnosis and TreatmentMDPI - Multidisciplinary Digital Publishing Institute20231 online resource (210 p.)3-0365-8650-4 This Special Issue covers recent research in nanochemistry convergence from disease prevention to diagnosis and treatment. It includes studies on new (bio)molecules and hybrids with diagnostic, chemopreventive, or therapeutical properties; novel nanobioengineered biosensors for disease diagnostics; and nanoparticles and nanobioconjugates for targeted drug delivery. The Special Issue collects a benchmark of state-of-the-art works on the computational simulation, structural modeling, and construction of new libraries of molecules to identify potential targets, synthesize molecules, and study their potential in developing diagnostic and therapeutic tools. It illustrates other topics that go from directed evolution techniques to help create mutants of proteins with enhanced activity concerning the native structures to reviews on nanobioprobes using conjugation approaches and biosensors as promising tools for disease detection. The Special Issue also provides examples of drug delivery systems based on biocompatible and biodegradable materials for chemoprevention.Converging NanochemistryTechnology: general issuesbicsscAndes virusantibodyanticancerantiproliferationAPN receptorapoptosisartificial intelligencebacterial nanocellulosebiomarker particlesbiopanningcancer biomarkerCDR randomizationcell deathchemopreventioncolon cancercolorectal cancerconjugation strategycontrolled drug delivery systemcovalent bondingdrug developmentdrug repurposingearly detectionelectrochemical glycobiosensorencapsulationepidermal growth factorfungal pathogensgenisteinglycanin situinfectious diseaseinflammationMEK inhibitorsmiRNAmolecular dockingnanobodynanomaterialnew therapeutic targetsnon-covalent bondingparasporinphage displayprotein modelingprotein structurereactive oxygen speciessite-directed mutagenesisstructural bioinformaticsstyrylquinolinessurface modificationsynthetic librarytumor necrosis factorvascular endothelial growth factorTechnology: general issuesBOOK9910743276003321Converging Nanochemistry: From Disease Prevention to Diagnosis and Treatment3560556UNINA