03014nam 2200901z- 450 991074327410332120230911(CKB)5690000000228567(oapen)doab113881(EXLCZ)99569000000022856720230920c2023uuuu -u- -engurmn|---annantxtrdacontentcrdamediacrrdacarrierChronic Kidney Disease: Underlying Molecular MechanismsMDPI - Multidisciplinary Digital Publishing Institute20231 online resource (216 p.)3-0365-8540-0 Chronic kidney disease (CKD) is a worldwide public health problem that must be addressed. The global increase in CKD prevalence is associated with an increase in conventional disease risk factors (e.g., diabetes and hypertension), which may be exacerbated by additional variables such as environmental and occupational exposure to toxic compounds. Authors contributed to this Special Issue by highlighting the finding of potential novel biomarkers of the disease and more effective therapy alternatives, as well as works that enhance the understanding of CKD pathogenesis and its related complications.Chronic Kidney DiseaseMedicine and NursingbicsscPharmacologybicsscadipose tissue browningarsenicbiomarkerscachexiacadmiumcellular injurychildrenchronic kidney diseaseCKDdevelopmental origins of health and disease (DOHaD)end-stage renal disease (ESRD)exercisefibrosisFSGSgrowth hormonegut microbiotaheavy metalshypertensioninflammationkidneylipolysislymphaticsMarinobufagenin (MBG)mass spectrometryMCDmercurymuscle functionmuscle massn/anervous and immune systemsNKCC1 transporterNZO miceoxidative stresspodocyte dysfunctionprebioticsprobioticsreactive oxygen species (ROS)SH045short-chain fatty acidsskeletal muscle wastingsodiumTNF-alphaTNFRtrimethylamine-N-oxideTRPC6uremic toxinsurine proteomeUUOMedicine and NursingPharmacologyBOOK9910743274103321Chronic Kidney Disease: Underlying Molecular Mechanisms3560539UNINA