01128nam a2200301 i 450099100075713970753620020507173206.0000705s1998 us ||| | eng 047155894Xb10753059-39ule_instLE01301869ExLDip.to Matematicaeng519.76AMS 90C27Cook, William J.534905Combinatorial optimization /William J. Cook ... [et al.]New York :J. Wiley & Sons,c1998x, 355 p. :ill. ;25 cmWiley-Interscience series in discrete mathematics and optimization"A Wiley-Interscience publication."Includes bibliographical references (p. 337-346) and indexCombinatorial optimization.b1075305923-02-1728-06-02991000757139707536LE013 90C COO11 (1998)12013000121789le013-E0.00-l- 08680.i1084666928-06-02Combinatorial optimization911328UNISALENTOle01301-01-00ma -engus 0104227nam 22006255 450 991074120070332120200703024625.01-4614-8869-910.1007/978-1-4614-8869-9(CKB)3710000000019064(EBL)1466746(SSID)ssj0001004905(PQKBManifestationID)11636712(PQKBTitleCode)TC0001004905(PQKBWorkID)11046792(PQKB)10703438(DE-He213)978-1-4614-8869-9(MiAaPQ)EBC1466746(PPN)172421322(EXLCZ)99371000000001906420130913d2013 u| 0engur|n|---|||||txtccrLeishmania and Leishmaniasis /by Awanish Kumar1st ed. 2013.New York, NY :Springer New York :Imprint: Springer,2013.1 online resource (90 p.)SpringerBriefs in Immunology,2194-2773 ;3Description based upon print version of record.1-4614-8868-0 Includes bibliographical references.Historical background of Leishmania and leishmaniasis -- Risk factors and definition of the problem -- Types of leishmaniasis -- Global status of visceral leishmaniasis -- Status of visceral leishmaniasis in India -- Morphology and Life cycle of Leishmania donovani -- Vectors and transmission of the disease -- Clinical symptoms of visceral leishmaniasis -- Control strategies of the disease -- Leishmania/HIV co-infections -- Host Immune response to Leishmania infection -- Cross-immunity between different Leishmania species -- Adoptive transfer of immunity -- Cutaneous leishmaniasis -- Mucocutaneous Leishmaniasis -- Visceral Leishmaniasis -- Post Kala-azar dermal Leishmaniasis -- Drugs against leishmaniasis -- Antimonials and Leishmaniasis -- SAG treatment, failure and resistance in Leishmania -- Vaccines against Leishmaniasis -- Strategy in practice for vaccine development against Leishmanisis.Leishmania-related illnesses remain among the world’s deadliest neglected tropical diseases, affecting approximately 12 million people in 88 countries. The mortality rate is substantial, contributing to nearly two million disability-adjusted life years. As more is understood about this parasite and its effects, work toward prevention, control, and treatment continues apace. Leishmania and Leishmaniasis will address the parasite and its attendant disease, which manifests in three syndromes: Visceral (VL), Cutaneous (CL) and Mucocutaneous Leishmaniasis (ML). The morphology and life cycles of the various species will be among the topics addressed in Part One. Part Two will focus on immunology, including host-immune response to Leishmania infection, cross-immunity between the different species and adoptive transfer of immunity. Parts Three and Four will address how Leishmania invade and survive, the clinical features of the disease, and its diagnosis.  Drugs, vaccines and treatment will be thoroughly explored, including experimental models of therapeutics. Leishmania and Leishmaniasis will provide a thorough examination of a parasite, the illnesses it causes and the misery it continues to visit upon large segments of the population.SpringerBriefs in Immunology,2194-2773 ;3ImmunologyParasitologyMedicineImmunologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B14000Parasitologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B19002Biomedicine, generalhttps://scigraph.springernature.com/ontologies/product-market-codes/B0000XImmunology.Parasitology.Medicine.Immunology.Parasitology.Biomedicine, general.610Kumar Awanishauthttp://id.loc.gov/vocabulary/relators/aut1424757BOOK9910741200703321Leishmania and Leishmaniasis3554253UNINA