01153nam0 22002771i 450 UON0049970920231205105408.99320191105d1996 |0itac50 baitaIT|||| |||||Pacio e Giovanni Bertini da Firenze e la bottega napoletana di Tino da CamainoGiulietta Chelazzi DiniPratoClaudio Martini1996133 p. in gran parte ill.28 cm.BERTINI GIOVANNIUONC095793FIBERTINI PACIOUONC095794FISCULTURAITALIA14 sec.UONC095795FI734.25Scultura gotica21CHELAZZI DINIGiuliettaUONV243026156494Martini ClaudioUONV283715650ITSOL20240220RICASIBA - SISTEMA BIBLIOTECARIO DI ATENEOUONSIUON00499709SIBA - SISTEMA BIBLIOTECARIO DI ATENEOSI ARTE GOTICO 15 SI FP 13332 7 Pacio e Giovanni Bertini da Firenze e la bottega napoletana di Tino da Camaino1564175UNIOR02664nam 2200565 a 450 991074118310332120200520144314.03-319-00303-810.1007/978-3-319-00303-0(CKB)2670000000371233(EBL)1317006(SSID)ssj0000894401(PQKBManifestationID)11436495(PQKBTitleCode)TC0000894401(PQKBWorkID)10835244(PQKB)10385878(DE-He213)978-3-319-00303-0(MiAaPQ)EBC1317006(PPN)170489531(EXLCZ)99267000000037123320130424d2013 uy 0engur|n|---|||||txtccrIron acquisition by the genus Mycobacterium history, mechanisms, role of siderocalin, anti-tuberculosis drug development /B. Rowe Byers, editor1st ed. 2013.Cham [Germany] New York Springer20131 online resource (96 p.)SpringerBriefs in molecular science. Biometals,2212-9901Description based upon print version of record.3-319-00302-X Includes bibliographical references and index.A History of Iron Metabolism in the Mycobacteria -- Mycobacterial Iron Uptake Mechanisms -- Siderocalin Combats Mycobacterial Infections -- Design of Anti-TB Drugs Using the Iron Uptake Platform.Iron Acquisition by the Genus Mycobacterium summarizes the early evidence for the necessity of iron in mycobacteria and the discovery of the mycobacterial siderophores mycobactin, carboxymycobactin, and exochelin. The structural characterization of the mycobacterial siderophores is described.  The genes so far identified as essential for iron acquisition and maintenance of an infection by pathogenic mycobacteria are discussed.  The potential role of siderocalin in iron gathering by M. tuberculosis is featured. Because new drugs for M. tuberculosis are needed, this brief also emphasizes the design of antibiotics that interfere with siderophore biosynthesis and the use of siderophore analogs and/or conjugates.SpringerBriefs in molecular science.Biometals.Iron proteinsMycobacteriaIron proteins.Mycobacteria.572.517Byers B. Rowe1762196MiAaPQMiAaPQMiAaPQBOOK9910741183103321Iron acquisition by the genus Mycobacterium4201977UNINA