03808nam 22006255 450 991073948700332120200705003257.01-4614-7351-910.1007/978-1-4614-7351-0(CKB)3710000000024276(EBL)1538540(SSID)ssj0001049048(PQKBManifestationID)11550205(PQKBTitleCode)TC0001049048(PQKBWorkID)11018905(PQKB)10355376(DE-He213)978-1-4614-7351-0(MiAaPQ)EBC1538540(PPN)176097988(EXLCZ)99371000000002427620131011d2013 u| 0engur|n|---|||||txtccrSmoking and Lung Inflammation[electronic resource] Basic, Pre-Clinical and Clinical Research Advances /edited by Thomas J. Rogers, Gerard J. Criner, William D. Cornwell1st ed. 2013.New York, NY :Springer New York :Imprint: Springer,2013.1 online resource (217 p.)Description based upon print version of record.1-4614-7350-0 Includes bibliographical references.Introduction -- Immunopathology of COPD -- Monocyte Populations Which Participate in Chronic Lung Inflammation -- Neutrophils Inflammation in COPD -- Role of Epithelial Cells in Chronic Inflammatory Lung Disease -- The Relationship Between Oxidative Stress Responses and Lung Inflammation with Cigarette Smoking -- Autoimmune Mechanisms Contributing to Chronic Obstructive Pulmonary Disease -- Chronic Obstructive Pulmonary Disease (COPD): Local and Systemic Disease -- Infectious Mechanisms Regulating Susceptibility to Acute Exacerbations of COPD -- COPD: Biomarkers and Phenotypes -- Anti-inflammatory Therapeutics in COPD: Past, Present and Future.Smoking and Lung Inflammation is the first book directly related to chronic lung inflammation of its kind in several respects. First, the it focuses on both basic and clinical research on COPD, and the inflammatory mechanisms that function in these diseases. Second, it is unique with respect to scope of the discussion of the unusual characteristics of the immune response which occurs in these patients. Third, it includes knowledge being gained from translational research conducted through clinical trials at several Medical Schools in the United States. Not only is this research providing information about novel drugs and therapies, but it is also advancing our understanding of the genetics of these diseases. This work will illuminate the molecular basis for these diseases, and hopefully will permit us to individualize the therapies for these diseases.ImmunologyRespiratory organs—DiseasesPathologyImmunologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B14000Pneumology/Respiratory Systemhttps://scigraph.springernature.com/ontologies/product-market-codes/H33134Pathologyhttps://scigraph.springernature.com/ontologies/product-market-codes/H4800XImmunology.Respiratory organs—Diseases.Pathology.Immunology.Pneumology/Respiratory System.Pathology.616.200471Rogers Thomas Jedthttp://id.loc.gov/vocabulary/relators/edtCriner Gerard Jedthttp://id.loc.gov/vocabulary/relators/edtCornwell William Dedthttp://id.loc.gov/vocabulary/relators/edtBOOK9910739487003321Smoking and Lung Inflammation3554610UNINA