01088cam0 2200277 450 E60020007026820200424083915.020101223d1979 |||||ita|0103 baitaITGli "Essayes" di Francis BaconStudio introduttivo, testo critico e commento Mario MelchiondaFirenzeOlschki1979VIII, 661 p.24 cmPubblicazioni della Facolta di lettere e filosofiaUniversità di Padova60001LAEC000292112001 *Pubblicazioni della Facolta di lettere e filosofia, Università di Padova60Bacon, Francis <1561-1626>AF00006428070159133Melchionda, MarioA600200062314070ITUNISOB20200424RICAUNISOBUNISOB10055390E600200070268M 102 Monografia moderna SBNM100004807Si55390acquistomassimoUNISOBUNISOB20101223091407.020200424083854.0SpinosaGli "Essayes" di Francis Bacon1700776UNISOB03351nam 2200601 a 450 991073944290332120200520144314.01-4614-7855-310.1007/978-1-4614-7855-3(CKB)2670000000530509(EBL)1398484(OCoLC)858763715(SSID)ssj0000986618(PQKBManifestationID)11586560(PQKBTitleCode)TC0000986618(PQKBWorkID)10942163(PQKB)11554079(DE-He213)978-1-4614-7855-3(MiAaPQ)EBC1398484(PPN)172420083(EXLCZ)99267000000053050920130717d2013 uy 0engur|n|---|||||txtccrProtein tyrosine phosphatase control of metabolism /Kendra K. Bence, editor1st ed. 2013.New York Springer20131 online resource (279 p.)Description based upon print version of record.1-4614-7854-5 1-4899-9798-9 Includes bibliographical references and index.Redox Regulation of PTPs in Metabolism: Focus on Assays -- Quantitative Modeling of PTPs and Implications for Studying Metabolic Signaling -- Protein-Tyrosine Phosphatase 1B Substrates and Control of Metabolism -- PTP1B and TCPTP in CNS Signaling and Energy Balance -- PTP1B in the Periphery: Regulating Insulin Sensitivity and ER Stress -- Role of Protein Tyrosine Phosphatase 1B in Hepatocyte-Specific Insulin and Growth Factor Signaling -- PTP1B in Obesity-Related Cardiovascular Runction -- Role of SHP2 Protein Tyrosine Phosphatase in Cardiac Metabolism -- Metabolic Effects of Neural and Pancreatic SHP2 -- Protein Tyrosine Phosphatase Epsilon as a Regulator of Body Weight and Glucose Metabolism -- The Role of LMPTP in the Metabolic Syndrome -- Mitogen-Activated Protein Kinase Phosphatases in Metabolism -- Glycogen Metabolism and Lafora Disease -- Index.Tyrosine phosphorylation is a rapid and reversible protein modification catalyzed by the yin and yang activities of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs).  A multitude of PTPs have been implicated in human disease, with a growing number of PTPs now known to play major roles in prevalent metabolic diseases including obesity and type 2 diabetes.  Recent studies into PTP function in the context of metabolism highlight the importance of understanding the specific substrates and binding partners of these enzymes, the regulation of PTP activity, and the cell/tissue specificity of PTP functions.  This volume contains chapters which highlight many aspects of PTP function in the context of metabolism.Protein-tyrosine phosphatasePhysiological effectMetabolismRegulationProtein-tyrosine phosphatasePhysiological effect.MetabolismRegulation.570572572.6610Bence Kendra K1754804MiAaPQMiAaPQMiAaPQBOOK9910739442903321Protein tyrosine phosphatase control of metabolism4191299UNINA