03222nam 22006015 450 991073372420332120230613192800.03-319-45618-010.1007/978-3-319-45618-8(CKB)3710000001045316(DE-He213)978-3-319-45618-8(MiAaPQ)EBC4800173(PPN)19887099X(EXLCZ)99371000000104531620170203d2017 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierProgress in the Chemistry of Organic Natural Products 104 /edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun'ichi Kobayashi1st ed. 2017.Cham :Springer International Publishing :Imprint: Springer,2017.1 online resource (V, 246 p. 240 illus., 69 illus. in color.) Progress in the Chemistry of Organic Natural Products,2192-4309 ;1043-319-45616-4 Includes bibliographical references at the end of each chapters.The first contribution describes apolar and polar molecular fossils and, in particular biomarkers, along the lines usually followed in organic chemistry textbooks, and points to their bioprecursors when available. Thus, the apolar compounds are divided in linear and branched alkanes followed by alicyclic compounds and aromatic and heterocyclic molecules, and, in particular, the geoporphyrins. The polar molecular fossils contain as functional groups or constituent units ethers, alcohols, phenols, carbonyl groups, flavonoids, quinones, and acids, or are polymers like kerogen, amber, melanin, proteins, or nucleic acids. The final sections discuss the methodology used and the fundamental processes encountered by the biomolecules described, including diagenesis, catagenesis, and metagenesis. The second contribution covers the distribution of phthalides in nature and the findings in the structural diversity, chemical reactivity, biotransformations, syntheses, and bioactivity of natural and semisynthetic phthalides.Progress in the Chemistry of Organic Natural Products,2192-4309 ;104Chemistry, OrganicPharmaceutical chemistryMedicinal chemistryOrganic ChemistryPharmaceuticsMedicinal ChemistryChemistry, Organic.Pharmaceutical chemistry.Medicinal chemistry.Organic Chemistry.Pharmaceutics.Medicinal Chemistry.547Kinghorn A. Douglasedthttp://id.loc.gov/vocabulary/relators/edtFalk Heinzedthttp://id.loc.gov/vocabulary/relators/edtGibbons Simonedthttp://id.loc.gov/vocabulary/relators/edtKobayashi Jun'ichiedthttp://id.loc.gov/vocabulary/relators/edtMiAaPQMiAaPQMiAaPQBOOK9910733724203321Progress in the Chemistry of Organic Natural Products 1043393769UNINA