02120nam 2200409z- 450 991034675030332120210212(CKB)4920000000094211(oapen)https://directory.doabooks.org/handle/20.500.12854/59417(oapen)doab59417(EXLCZ)99492000000009421120202102d2018 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierSingle-Domain Antibodies: Biology, Engineering and Emerging ApplicationsFrontiers Media SA20181 online resource (338 p.)Frontiers Research Topics2-88945-432-0 Single-domain antibodies (sdAbs) represent the minimal antigen binding-competent form of the immunoglobulin domain and have unique properties and applications. SdAbs are naturally produced as the variable domains of the heavy chain-only antibodies of camelid ruminants and cartilaginous fishes, but can also be engineered synthetically from autonomous human or mouse VH or VL domains. The scope of this research topic and associated e-book covers current understanding and new developments in (i) the biology, immunology and immunogenetics of sdAbs in camelids and cartilaginous fishes, (ii) strategies for sdAb discovery, (iii) protein engineering approaches to increase the solubility, stability and antigen-binding affinity of sdAbs and (iv) specialized applications of sdAbs in areas such diagnostics, imaging and therapeutics.Single-Domain AntibodiesMedicine and Nursingbicsscantibody discoveryantibody engineeringdiagnostic antibodysingle-domain antibodytherapeutic antibodyMedicine and NursingKevin A. Henryauth1279436C. Roger MacKenzieauthBOOK9910346750303321Single-Domain Antibodies: Biology, Engineering and Emerging Applications3015375UNINA03894nam 22006855 450 991072894500332120251009073529.0981-9917-86-710.1007/978-981-99-1786-0(MiAaPQ)EBC30562435(Au-PeEL)EBL30562435(OCoLC)1381708472(DE-He213)978-981-99-1786-0(BIP)089230687(PPN)272272116(CKB)26821629100041(EXLCZ)992682162910004120230601d2023 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierConstructional Viscoelastic Composite Materials Theory and Application /by Pouria Hajikarimi, Alireza Sadat Hosseini1st ed. 2023.Singapore :Springer Nature Singapore :Imprint: Springer,2023.1 online resource (170 pages)Print version: Hajikarimi, Pouria Constructional Viscoelastic Composite Materials Singapore : Springer,c2023 9789819917853 1. Introduction -- 2. Viscoelasticity Theoretical Background -- 3. Nonlinear Viscoelasticity -- 4. Experimental Characterization -- 5. 5. Analytical and Empirical For-mulation.Viscoelasticity is a complicated theorem that is generally used in several aspects of material characterization and modeling of polymers, resins, fiber-reinforced composites, bituminous composites, etc. On the other hand, the heterogeneous nature of composites like asphalt concrete and fiber-reinforced polymers has motivated lots of researchers to investigate the mechanical and rheological properties of these materials. This book mainly consists of the theory and application of viscoelastic materials used for construction. It starts with a comprehensible presentation of the theory of linear and nonlinear viscoelasticity. Wherein, the application of viscoelastic equations and principles on constructional viscoelastic composite materials considering time, temperature, loading rate dependency, and heterogeneity of composite substances is highlighted. The principles and equations of the viscoelasticity theorem are presented in several books, but here it is tried to present them more understandable and straightforwardly. This helps in solving real problems of heterogeneous composite materials, especially those which are used in construction. Moreover, the fundamental experiments for characterizing the elastic and viscoelastic properties of fibrous and bituminous composites are introduced and summarized. Then after, some analytical and empirical formulations for deriving the material properties of composites from the properties of the basic constituents are presented. These are followed by numerical simulation techniques using the finite element method to simulate composite materials.Continuum mechanicsBuilding materialsMaterialsAnalysisPolymersRheologyContinuum MechanicsBuilding MaterialsMaterials Characterization TechniquePolymersRheologyContinuum mechanics.Building materials.MaterialsAnalysis.Polymers.Rheology.Continuum Mechanics.Building Materials.Materials Characterization Technique.Polymers.Rheology.624.18Hajikarimi Pouria1367153Sadat Hosseini Alireza1367154MiAaPQMiAaPQMiAaPQBOOK9910728945003321Constructional Viscoelastic Composite Materials3389878UNINA