02088oam 2200577 450 991071549270332120210318092636.0(CKB)5470000002511113(OCoLC)681889444(OCoLC)622010748(OCoLC)667889459(OCoLC)974647401(OCoLC)1129134293(OCoLC)995470000002511113(EXLCZ)99547000000251111320101117d1992 ua 0engurbn|||||||||txtrdacontentcrdamediacrrdacarrierComparison of conventional onsite recorders and satellite telemetry for surface-water data collection by the U.S. Geological Survey /by Charles Parrett and E.F. Hubbard, JrHelena, Montana :U.S. Geological Survey,1992.1 online resource (iii, 30 pages) illustrationsWater-resources investigations report ;92-4060"August 1992."Includes bibliographical references (page 18).HydrologyUnited StatesRemote sensingGeophysical instrumentsEvaluationWater-supplyUnited StatesRemote sensingHydrologyRemote sensingfastWater-supplyRemote sensingfastUnited StatesfastHydrologyRemote sensing.Geophysical instrumentsEvaluation.Water-supplyRemote sensing.HydrologyRemote sensing.Water-supplyRemote sensing.Parrett Charles1387789Hubbard E. F.Geological Survey (U.S.),OCLCEOCLCEOCLCQOCLCFOCLCOOCLCQOCLCOOCLCQCOPGPOBOOK9910715492703321Comparison of conventional onsite recorders and satellite telemetry for surface-water data collection by the U.S. Geological Survey3541362UNINA03735nam 22005295 450 991025391360332120200705115637.03-658-18623-210.1007/978-3-658-18623-4(CKB)3710000001411701(DE-He213)978-3-658-18623-4(MiAaPQ)EBC4872972(PPN)202989550(EXLCZ)99371000000141170120170606d2017 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierImpact of Survivin Acetylation on its Biological Function /by David Dannheisig1st ed. 2017.Wiesbaden :Springer Fachmedien Wiesbaden :Imprint: Springer Spektrum,2017.1 online resource (XXIII, 104 p. 41 illus., 10 illus. in color.) BestMasters,2625-35773-658-18622-4 Apoptosis – The Programmed Suicide -- Cancer – The Enemy Inside -- Nucleocytoplasmic Transport– Cellular Navigation -- Biological Function of Survivin -- Protein modification – Make-Up for Proteins -- Cell cycle – Virchow’s Heritage.In his research, David Dannheisig investigates the influence of lysine129 acetylation on the biological function of survivin including alteration of nucleocytoplasmic shuttling as well as dimerization behavior. Since survivin participates in two major hallmarks of oncogenesis, namely cell death inhibition and chromosomal segregation during the cell cycle, it reflects a valuable target in cancer therapy and research. The author establishes proximity-dependent, fluorescence-microscopic methods to quantify the interaction of survivin with the export receptor Crm1 as well as the homodimerization itself. In the future, those systems can be used to examine the feasible effect of chemical modulators which are targeting these interactions in a cellular background. The outcome achieved is an essential step towards the enhancement of potential cancer therapies. Contents Apoptosis – The Programmed Suicide Cancer – The Enemy Inside Nucleocytoplasmic Transport– Cellular Navigation Biological Function of Survivin Protein modification – Make-Up for Proteins Cell cycle – Virchow’s Heritage Target Groups Lecturers, students and researchers in the biological-medical sector Practitioners in the fields of molecular biology, cell biology, fluorescence microscopy, medical biology, protein interaction studies The Author David Dannheisig currently is a student of the International Graduate School in Molecular Medicine (IGradU) pursuing his PhD (Dr. rer. nat) degree at the Institute of Biochemistry and Molecular Biology (iBMB) at Ulm University, Germany.BestMasters,2625-3577Cancer researchBiomedical engineeringCell biologyCancer Researchhttps://scigraph.springernature.com/ontologies/product-market-codes/B11001Biomedical Engineering/Biotechnologyhttps://scigraph.springernature.com/ontologies/product-market-codes/B24000Cell Biologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L16008Cancer research.Biomedical engineering.Cell biology.Cancer Research.Biomedical Engineering/Biotechnology.Cell Biology.614.5999Dannheisig Davidauthttp://id.loc.gov/vocabulary/relators/aut937024BOOK9910253913603321Impact of Survivin Acetylation on its Biological Function2110401UNINA