04249oam 2200565 450 991013710090332120230621140712.0(CKB)3710000000824693(oapen)https://directory.doabooks.org/handle/20.500.12854/42565(EXLCZ)99371000000082469320191103h20152015 fy| 0engurc|#---|||||txtrdacontentcrdamediacrrdacarrierThe CA3 region of the hippocampus how is it? what is it for? how does it do it? /edited by Enrico Cherubini and Richard MilesFrontiers Media SA2015[Lausanne, Switzerland] :Frontiers Media SA,[2015]©20151 online resource (165 pages) illustrations (chiefly colour); digital file(s)Frontiers Research TopicsPrint version: The CA3 region of the hippocampus. [Lausanne, Switzerland] : Frontiers Media SA, 2015 2889196313 Includes bibliographical references.The CA3 hippocampal region receives information from the entorhinal cortex either directly from the perforant path or indirectly from the dentate gyrus via the mossy fibers (MFs). According to their specific targets (principal/mossy cells or interneurons), MFs terminate with large boutons or small filopodial extensions, respectively. MF-CA3 synapses are characterized by a low probability of release and pronounced frequency-dependent facilitation. In addition MF terminals are endowed with mGluRs that regulate their own release. We will describe the intrinsic membrane properties of pyramidal cells, which can sometimes fire in bursts, together with the geometry of their dendritic arborization. The single layer of pyramidal cells is quite distinct from the six-layered neocortical arrangement. The resulting aligned dendrites provides the substrate for laminated excitatory inputs. They also underlie a precise, diversity of inhibitory control which we will also describe in detail. The CA3 region has an especially rich internal connectivity, with recurrent excitatory and inhibitory loops. In recent years both in vivo and in vitro studies have allowed to better understand functional properties of the CA3 auto-associative network and its role in information processing. This circuit is implicated in encoding spatial representations and episodic memories. It generates physiological population synchronies, including gamma, theta and sharp-waves that are presumed to associate firing in selected assemblies of cells in different behavioral conditions. The CA3 region is susceptible to neurodegeneration during aging and after stresses such as infection or injury. Loss of some CA3 neurones has striking effects on mossy fiber inputs and can facilitate the generation of pathologic synchrony within the CA3 micro-circuit. The aim of this special topic is to bring together experts on the cellular and molecular mechanisms regulating the wiring properties of the CA3 hippocampal microcircuit in both physiological and pathological conditions, synaptic plasticity, behavior and cognition. We will particularly emphasize the dual glutamatergic and GABAergic phenotype of MF-CA3 synapses at early developmental stages and the steps that regulate the integration of newly generated neurons into the adult dentate gyrus-CA3 circuit.Frontiers research topics.Hippocampus (Brain)Hippocampus (Brain)PhysiologyNeurobiologyNeurosciencesepisodic memorymossy fibersAssociative networkspatial representationCA3 subfieldHippocampusTheta RhythmHippocampus (Brain)Hippocampus (Brain)Physiology.Neurobiology.Neurosciences.612.825Enrico Cherubiniauth1364363Cherubini EnricoMiles Richard1951-UkMaJRUBOOK9910137100903321The CA3 region of the hippocampus3385570UNINA02268oam 2200637 450 991070587100332120170725084302.0(CKB)5470000002453705(OCoLC)891581391(OCoLC)995470000002453705(EXLCZ)99547000000245370520140929d1970 ua 0engurmn|||||||||txtrdacontentcrdamediacrrdacarrierChronology of emplacement of Mesozoic batholithic complexes in California and western Nevada /by J. F. Evernden and R. W. Kistler; prepared in cooperation with the University of California (Berkeley) Department of Geological SciencesWashington :United States Department of the Interior, Geological Survey,1970.1 online resource (iv, 42 pages) illustrations, maps +2 platesGeological Survey professional paper ;623Title from title screen (viewed September 24, 2014).Includes bibliographical references (pages 26-28).BatholithsCaliforniaBatholithsNevadaGeologyCaliforniaGeologyNevadaGeology, StratigraphicMesozoicBatholithsfastGeologyfastGeology, StratigraphicfastMesozoic Geologic PeriodfastCaliforniafastNevadafastBatholithsBatholithsGeologyGeologyGeology, StratigraphicBatholiths.Geology.Geology, Stratigraphic.Mesozoic Geologic Period.Evernden J. F.1922-1403195Kistler Ronald Wayne1931-Geological Survey (U.S.),University of California, Berkeley.Department of Geological Sciences.COPCOPOCLCOOCLCFGPOBOOK9910705871003321Chronology of emplacement of Mesozoic batholithic complexes in California and western Nevada3475340UNINA01968nam 2200457 450 991071351500332120200603165149.0(CKB)5470000002502517(OCoLC)1156609890(EXLCZ)99547000000250251720200603j197811 ua 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierEvaluation of a proposed Colorado state inspection/maintenance program /by Thomas C. Bejma[Ann Arbor, Mich.] :Technology Assessment and Evaluation Branch, Emission Control Technology Division, Office of Mobile Source Air Pollution Control, Office of Air, Noise and Pollution, U.S. Environmental Protection Agency,November, 1978.1 online resource (approximately 14 pages) illustrations"November, 1978.""79-2."Report number assigned by the National Service Center for Environmental Publications (NSCEP); TAEB792.Motor vehiclesInspectionColoradoMotor vehiclesMaintenance and repairMotor vehiclesColoradoTestingMotor vehiclesMotorsExhaust gasMeasurementAltitudesTechnical reports.lcgftMotor vehiclesInspectionMotor vehiclesMaintenance and repair.Motor vehiclesTesting.Motor vehiclesMotorsExhaust gasMeasurement.Altitudes.Bejma Thomas C.1404026United States.Environmental Protection Agency.Office of Mobile Source Air Pollution Control.Emission Control Technology Division.Technology Assessment and Evaluation Branch,GPOGPOBOOK9910713515003321Evaluation of a proposed Colorado state inspection3533896UNINA