03441oam 2200589 450 991070347350332120230421054934.01-4615-5901-410.1007/978-1-4615-5901-6(CKB)3390000000041086(SSID)ssj0001086182(PQKBManifestationID)11690895(PQKBTitleCode)TC0001086182(PQKBWorkID)11056153(PQKB)10638506(DE-He213)978-1-4615-5901-6(MiAaPQ)EBC5588150(MiAaPQ)EBC6491770(Au-PeEL)EBL5588150(OCoLC)1066197055(OCoLC)1003050715(EXLCZ)99339000000004108620210727d1997 uy 0engurnn|008mamaatxtccrSubcellular biochemistryVolume 28Cholesterol its functions and metabolism in biology and medicine /edited by Robert Bittman1st ed. 1997.New York :Springer Science + Business Media, LLC,1997.1 online resource (XXVIII, 548 p.) Subcellular Biochemistry,0306-0225 ;28Includes index.0-306-45478-5 1-4613-7707-2 1 Signaling Molecules Derived from the Cholesterol Biosynthetic Pathway -- 2 Coordinate Regulation of Cholesterol 7?-Hydroxylase and HMG-CoA Reductase in the Liver -- 3 Polyprenyl Diphosphate Synthases -- 4 Antifungal Sterol Biosynthesis Inhibitors -- 5 The Smith-Lemli-Opitz Syndrome: A Potentially Fatal Birth Defect Caused by a Block in the Last Enzymatic Step in Cholesterol Biosynthesis -- 6 Has Nature Designed the Cholesterol Side Chain for Optimal Interaction with Phospholipids? -- 7 Cholesterol and Myelin -- 8 Regulation of Mitochondrial Cholesterol Metabolism -- 9 Lipoproteins and Cellular Cholesterol Homeostasis -- 10 Cholesterol-Sphingomyelin Interactions in Cells—Effects on Lipid Metabolism -- 11 Mechanisms and (Patho)Physiological Significance of Biliary Cholesterol Secretion -- 12 Cholesterol Deposition in Atherosclerotic Lesions -- 13 Cholesterol Metabolism and Tumor Cell Proliferation -- 14 Biological Implications of the Niemann-Pick C Mutation -- 15 Sitosterolemia -- 16 Cholesterol Cytochemistry in Cell Biology and Disease -- 17 Approaches for the Design of Novel Anti-Atherogenic Compounds.Experts investigate the biochemical and biomedical aspects of cholesterol, addressing its metabolism in normal and disease states. They discuss a broad range of topics, including key steps in the cholesterol biosynthetic pathway, and the role of cholesterol in cancer, atherosclerosis, and diseases of the nervous system. The book's comprehensive coverage also includes the pathological consequences and potential therapies for various disease states, and the development of new anti-atherogenic drugs.Subcellular Biochemistry,0306-0225 ;28CholesterolMetabolismPopular works.fastCholesterolMetabolism.612.12Bittman RobertUnited States.Food and Drug Administration.Office of Women's Health,MiAaPQMiAaPQUtOrBLWBOOK9910703473503321Subcellular biochemistry809898UNINA