01899nam 2200373 450 991068841810332120230623121215.0(CKB)5400000000040557(NjHacI)995400000000040557(EXLCZ)99540000000004055720230623d2020 uy 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierAmyotrophic Lateral Sclerosis /edited by Muralidhar L. HegdeLondon, United Kingdom :IntechOpen,2020.1 online resource (160 pages) illustrations1-83880-582-6 A flurry of recent research on the role of the RNA/DNA-binding proteins TDP-43 and FUS as well as a dozen other factors (e.g., C9ORF72 and profilin) has led to a new paradigm in our understanding of the pathobiology of the motor neuron disease, Amyotrophic Lateral Sclerosis (ALS). How these factors trigger neuromuscular dysfunction is critical for developing more effective ALS therapeutics. The 'gain-of-toxicity' or 'loss-of-function' of these etiological factors is a key question. Recent studies on the imbalance in genome damage versus repair have opened avenues for potential DNA repair-based therapeutics. This book highlights emerging science in the area of ALS and discusses key approaches and mechanisms essential for developing a cure for ALS.Amyotrophic Lateral Sclerosis Amyotrophic lateral sclerosisAmyotrophic lateral sclerosisTreatmentAmyotrophic lateral sclerosis.Amyotrophic lateral sclerosisTreatment.616.83Hegde Muralidhar L.NjHacINjHaclBOOK9910688418103321Amyotrophic lateral sclerosis2004420UNINA03323nam 22006135 450 991074629720332120230922104104.0981-9922-09-710.1007/978-981-99-2209-3(MiAaPQ)EBC30751958(Au-PeEL)EBL30751958(DE-He213)978-981-99-2209-3(PPN)272738360(CKB)28283993100041(EXLCZ)992828399310004120230922d2023 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierBiotechnological Interventions Augmenting Livestock Health and Production /edited by Chandra Sekhar Mukhopadhyay, Ratan Kumar Choudhary, Harsh Panwar, Yashpal Singh Malik1st ed. 2023.Singapore :Springer Nature Singapore :Imprint: Springer,2023.1 online resource (463 pages)Livestock Diseases and Management,2662-4354Print version: Mukhopadhyay, Chandra Sekhar Biotechnological Interventions Augmenting Livestock Health and Production Singapore : Springer,c2023 9789819922086 Module 1_Functional Genomics and Proteomics -- Module 2_Microbial Genomics and Novel Biotechnological approaches to enhance animal health -- Module 3_Bioinformatics, Big Data, and Integrated Omics.This book comprehensively discusses the applications of molecular genetics, functional and structural genomics, and proteomics vis-a-vis bioinformatics, artificial intelligence, and robotics in livestock healthfulness and productivity. It reviews the biotechnological approaches in veterinary sciences for increasing productivity and resistance to disease. The book emphasizes the approaches based on artificial intelligence to analyze the data collected on animals, pathogens, and their environment. It underscores artificial intelligence applications in disease diagnosis, epidemiological studies, and detecting biological phenomena, including heat-detection, pregnancy, docility, and infections. Further, the book examines the genomics and proteomics approaches for understanding the gut microbiota and the role of pathogen-host interactions in animal health and disease. Lastly, it explores both pathogenic and non-pathogenic microbial transfer between humans, animals, and the environment across one health spectrum.Livestock Diseases and Management,2662-4354Veterinary medicineGeneticsBiotechnologyVeterinary ScienceGenetics and GenomicsBiotechnologyVeterinary medicine.Genetics.Biotechnology.Veterinary Science.Genetics and Genomics.Biotechnology.636.089Mukhopadhyay Chandra Sekhar1429543Choudhary Ratan Kumar1429544Panwar Harsh1429545Malik Yashpal Singh1075314MiAaPQMiAaPQMiAaPQBOOK9910746297203321Biotechnological Interventions Augmenting Livestock Health and Production3568546UNINA01264nam2 2200289 i 450 VAN0003806620240806100405.92188-348-4662-120050722d2005 |0itac50 baitaIT|||| |||||ˆ3.2: I ‰contratti bancariGiuseppe FaucegliaTorinoGiappichelli[2005]XII, 567 p.24 cm.001VAN000106612001 Trattato di diritto commercialediretto da Vincenzo Buonocore[poi] diretto da Renzo Costi.3.2TorinoVANL000001FaucegliaGiuseppeVANV001509116475Giappichelli <editore>VANV107921650ITSOL20240906RICABIBLIOTECA DEL DIPARTIMENTO DI ECONOMIAIT-CE0106VAN03BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZAIT-CE0105VAN00VAN00038066BIBLIOTECA DEL DIPARTIMENTO DI GIURISPRUDENZA00CONS VI.Eg.147 00 30263 20050722 BIBLIOTECA DEL DIPARTIMENTO DI ECONOMIA03PREST IVCf23 03 7525 20070309 Contratti bancari758299UNICAMPANIA