02244nam 2200373 450 991068831290332120230623212609.010.5772/intechopen.73968(CKB)5400000000041923(NjHacI)995400000000041923(EXLCZ)99540000000004192320230623d2020 uy 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierSarcoidosis and granulomatosis diagnosis and management /Mohammad Hosein Motamedi, editorLondon :IntechOpen,2020.1 online resource (178 pages)1-83962-834-0 Includes bibliographical references.Sarcoidosis is a multi-organ, granulomatous disease the etiology of which remains unknown. It is characterized by T-cell dysfunction and B-cell hyperactivity with increased local immune activity and inflammation that leads to the formation of noncaseating granulomas in the organs involved. The lung and lymphatic system are the most commonly affected organs, however virtually any organ may be affected. Other common sites of involvement include the skin, eye, central nervous system, and the heart. Patients may present different symptoms related to the disease stage and the specific organ involved. Sarcoidosis is a global disease, and its prevalence has increased twofold over the past years. Due to the clinical heterogeneity and variable diagnostic criteria in different countries, it is difficult to calculate the exact prevalence and incidence of sarcoidosis. Age, sex, race, and geographic origin significantly influence the incidence of sarcoidosis. The book at hand seeks to assess the current diagnostic techniques, imaging techniques, differential diagnosis of this disease, as well as other granulomatous diseases mimicking sarcoidosis.Sarcoidosis and Granulomatosis SarcoidosisSarcoidosis.616.429Motamedi Mohammad HoseinNjHacINjHaclBOOK9910688312903321Sarcoidosis and granulomatosis2951507UNINA