02740nam 2200421 450 991064723090332120230327090502.03-0365-6334-2(CKB)5680000000300035(NjHacI)995680000000300035(EXLCZ)99568000000030003520230327d2023 uy 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierAdditive manufacturing (AM) for advanced materials and structures green and intelligent development trend /edited by Hao Yi, Huajun Cao, Menglin Liu[Place of publication not identified] :MDPI - Multidisciplinary Digital,[2023]©20231 online resource (304 pages)3-0365-6335-0 Additive manufacturing (AM), as an advanced manufacturing technology, has overturned the traditional concept of subtractive manufacturing. It has revolutionized advanced integrated structural design, high-performance material preparation, and the manufacturing of complex components. AM technology is changing the way products are developed, produced, and commercialized, leading to disruptive changes in the economy and society. AM technology has received extensive attention and research from the research community since its inception, and it is leading manufacturing technology and continues to be used with great effectiveness in the aerospace industry, automotive industry, medical plant applications, and many other fields. However, the development of additive manufacturing still faces demanding technical challenges; for example, due to insufficient process planning and inadequate process control, many defects are often observed in the products of AM processes, reducing production efficiency and deteriorating product quality. To promote AM technology toward high efficiency, high precision, high performance, and low cost in a green and intelligent direction, many advanced design and manufacturing technologies are in urgent need of further breakthroughs, such as numerical and analytical models for structural design, experimental methods, performance prediction, and process optimization.Additive Manufacturing Manufacturing processesManufacturing industriesManufacturing processes.Manufacturing industries.670Yi HaoCao HuajunLiu MenglinNjHacINjHaclBOOK9910647230903321Additive manufacturing (AM) for advanced materials and structures3085183UNINA03012nam 2200529z- 450 991068825160332120220419(CKB)5700000000080386(oapen)https://directory.doabooks.org/handle/20.500.12854/80894(oapen)doab80894(EXLCZ)99570000000008038620202204d2021 |y 0spaurmn|---annantxtrdacontentcrdamediacrrdacarrierExpedición para la construcción de paz «Latinpaz»ColombiaUniversidad Santiago de Cali20211 online resource (144 p.)958-51-4793-9 Al comenzar la labor de prologar este libro me encontré en una posición familiar para mí: sin saber qué hacer. Y, ante la ignorancia y el no conocimiento del siguiente paso, pensé: ¿Qué es lo que hace un investigador? Pues curiosea, investiga, pregunta, hasta que descubre cual es el siguiente paso, que es lo que toca hacer ahora. Y en la búsqueda está el camino. En la investigación el investigador se va formando a sí mismo, impulsado por dos cosas: 1) El reconocimiento de que no sabe y 2) El querer saber. La humildad académica y la curiosidad son el combustible y motor del investigador, sin ellos la investigación no existe. En el momento en el que se tiene una actitud de "saberlo todo" el camino se ha terminado. Rosaura Rojas Monedero es una investigadora, ya que en ella están presentes ambos elementos, junto con un tercero muy particular, que si se combina con la humildad académica y la curiosidad se logran resultados extraordinarios: la pasión. Rosaura es una mujer apasionada por saber, por investigar, y sobre todo por lograr lo que se propone. Tuve la fortuna de conocer este proyecto desde su génesis, cuando una estudiante del Doctorado en Métodos Alternos de Solución de Conflictos de la Facultad de Derecho y Criminología de la Universidad Autónoma de Nuevo León, del cual soy egresada, me contactó buscando una guía adicional para la elaboración de su tesis.Peace studies & conflict resolutionbicsscMexicofastColombiafastAulasAutocontrolColombiaConstrucción de pazConvivenciaDesarrollo socioemocionalEducaciónEscuelas públicasIntervenciónLatinpazMéxicoPazPreadolescenciaSolución de conflictosPeace studies & conflict resolutionRojas Monedero Rosauraauth1351313Rojas Monedero RosauraedtRojas Monedero RosauraothBOOK9910688251603321Expedición para la construcción de paz «Latinpaz»3097464UNINA03195nam 2200481z- 450 991026114030332120210211(CKB)4100000002484689(oapen)https://directory.doabooks.org/handle/20.500.12854/42315(oapen)doab42315(EXLCZ)99410000000248468920202102d2017 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierBK Channels: Integrators of Cellular Signals in Health and DiseaseFrontiers Media SA20171 online resource (183 p.)Frontiers Research Topics2-88945-291-3 Maxi calcium-activated potassium channels (BK) are an amazing category of ion channels which are found in cellular plasma membranes as well as in membranes of intracellular organelles. The function of these channels is to repolarize any excited membrane by passing a potassium outward current, in response to depolarization and/or increase in local calcium levels. Thus, voltage and calcium ions are involved in gating the channel under physiological conditions. This dual activation makes them perfect sensors for many cellular events that require integration between intracellular calcium levels and electrical signals. A plethora of physiological and pathophysiological functions, such as membrane hyperpolarization, modulation of synaptic transmission, hormone secretion or mental deficiencies, vaso-regulation, epilepsies, heart diseases, myotonic dystrophies, hypertension etc, in almost all cells and tissues were reported for these channels. BK channels are main targets for important ligands like alcohol and gaseous neurotransmitters, such as NO, CO or H2S, to name a few. In the last years, the molecular entities and mechanisms involved in modulation of BK channels have gained tremendous attention, as the key role of these channels in cellular processes became increasingly recognized. Indeed, accessory proteins such as slob, beta and gamma subunits, all serve to modulate the channel gating characteristics. Moreover, channel subunit expression and function is further tuned by phosphorylation/ dephosphorylation processes, redox mechanisms and the lipid microenvironment of the BK channel protein complex. This e-book contains structural and functional aspects of BK channels, channel modulation by a variety of agents and cellular components, as well as the channel's relevance in health and disease.BK ChannelsPhysiologybicsscBK channeldiseaseethanolhealthhydrogensulfideischemiaKCNMA1maxi calcium activated potassium channelnervous systemSloPhysiologyAlex Dopicoauth1311561Thomas M. WeigerauthAnton HermannauthBOOK9910261140303321BK Channels: Integrators of Cellular Signals in Health and Disease3030422UNINA