01945nam 2200385 450 991068820830332120230625095934.0(CKB)5400000000045552(NjHacI)995400000000045552(EXLCZ)99540000000004555220230625d2021 uy 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierMuscle cell and tissue novel molecular targets and current advances /edited by Kunihiro Sakuma, Nobuo MorotomiLondon :IntechOpen,[2021]©20211 online resource (130 pages) illustrations1-83968-652-9 Includes bibliographical references.The loss of skeletal muscle mass and strength substantially impairs physical performance and quality of life. This book details some approaches to the treatment of muscle wasting. It also reviews novel applications against pulmonary arterial hypertension such as cell reprogramming and the use of anticancer drugs that induce programmed cell death. Vascular smooth muscle cells (VSMCs) are the most prevalent cell types in blood vessels and serve critical regulatory roles. This publication also introduces mathematical models concerning the molecular mechanism and targets of cyclic guanosine 3',5'-monophosphate (cGMP) in the contraction of VSMCs. This book will be of interest to professionals in clinical practice, medical and health care students, and researchers working in muscle-related fields of science.Muscle Cell and Tissue MusclesDiseasesMusclesDiseases.616.74Sakuma KunihiroMorotomi NobuoNjHacINjHaclBOOK9910688208303321Muscle Cell and Tissue2280361UNINA