01372nam 2200421 450 991015862160332120230808201230.01-63431-103-51-63431-102-7(CKB)3710000001008211(MiAaPQ)EBC4775434(EXLCZ)99371000000100821120170117h20162016 uy 1engurcnu||||||||rdacontentrdamediardacarrierThe enchanted globe /Sean FairclothDurham, North Carolina :Imp Works,2016.©20161 online resource (233 pages)1-63431-101-9 Traveling from continent to continent amid hair-raising adventures and thrilling escapes, eleven-year-old Brendan, together with his younger brother Ryan and friend Gabrielle, must solve clues to defeat McGrab, a horrifying creature who wishes to conquer the world.Voyages and travelsFictionGeographyFictionVoyages and travelsGeography813.008032JUV037000bisacshFaircloth Sean1244912MiAaPQMiAaPQMiAaPQBOOK9910158621603321The enchanted globe2887680UNINA03323nam 2200481 450 991068678840332120230731000300.09783031243233(electronic bk.)978303124322610.1007/978-3-031-24323-3(MiAaPQ)EBC7233709(Au-PeEL)EBL7233709(OCoLC)1376934127(DE-He213)978-3-031-24323-3(PPN)269660062(EXLCZ)992638812910004120230731d2023 uy 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierSpray drying of vaccines from laboratory research to industrial applications /Cordin ArpagausFirst edition 2023.Cham, Switzerland :Springer Nature Switzerland AG,[2023]©20231 online resource (610 pages) illustrationsPrint version: Arpagaus, Cordin Spray Drying of Vaccines Cham : Springer International Publishing AG,c2023 9783031243226 Includes bibliographical references.Chapter 1 A short introduction to vaccines -- Chapter 2 Thermostability of vaccines -- Chapter 3 Drying technologies for vaccines -- Chapter 4 Aseptic spray drying technology -- Chapter 5 Design of experiment studies and scale-up -- Chapter 6 Applications of spray dried vaccines.-Chapter 7 Conclusions and future perspectives of spray-dried vaccines.This book addresses the stabilization of vaccine powders by spray drying and provides an overview of the current state of the art on a laboratory and industrial scale. The book aims to familiarize readers with the advances in vaccine spray drying technology to understand its application potential better. In particular, the book addresses the design of aseptic spray dryers, parameters affecting the spray drying process, sterile powder processing, cleaning procedures, and powder filling. In addition, different drying technologies for the production of dry powder vaccines are compared to discuss the unique capabilities of spray drying as a particle technology for vaccines. Special attention is given to research studies on spray-dried vaccines published over the past 30 years, with key findings from laboratory research to clinical trials. Potential applications of spray-dried vaccines and routes of administration are presented in detail. Finally, an outlook is given on how close the aseptic spray-drying of vaccines is to the market and the challenges that need to be overcome to be commercially successful. The book's target audience is academics, researchers, vaccine developers, industry experts, students, and possibly funders, including government agencies, who are active in the field. In addition, the book is a reference source for those involved in the vaccine formulation and biopharmaceutical processing industry.Spray dryingVaccinesBiotechnologySpray drying.VaccinesBiotechnology.660.28426Arpagaus Cordin1349776MiAaPQMiAaPQMiAaPQ9910686788403321Spray Drying of Vaccines3087599UNINA